Evidence map›Paper›PMID 29743623›Full record

ArticleScientific reports2018

In vivo Molecular Imaging of Glutamate Carboxypeptidase II Expression in Re-endothelialisation after Percutaneous Balloon Denudation in a Rat Model.

Heike Endepols, Felix M Mottaghy, Sakine Simsekyilmaz, Jan Bucerius, Felix Vogt, Oliver Winz, Raphael Richarz, Philipp Krapf, Bernd Neumaier, Boris D Zlatopolskiy and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Non-invasive molecular imaging of kidney diseases.Nature reviews. Nephrology · 2021
    Review
  2. High uptake ofEJNMMI research · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Heike EndepolsInstitute of Radiochemistry and Experimental Molecular Imaging (IREMB), University Hospital of Cologne, 50937, Cologne, Germany.ORCID 0000-0002-6166-4818
Felix M MottaghyDepartment of Nuclear Medicine, University Hospital, RWTH Aachen, 52074, Aachen, Germany. fmottaghy@ukaachen.de.
Sakine SimsekyilmazInstitute for Molecular Cardiovascular Research, University Hospital, RWTH Aachen, 52074, Aachen, Germany.
Jan BuceriusDepartment of Nuclear Medicine, University Hospital, RWTH Aachen, 52074, Aachen, Germany.
Felix VogtDepartment of Cardiology, Pneumology, Angiology, and Internal Intensive Care Medicine, University Hospital, RWTH Aachen, 52074, Aachen, Germany.
Oliver WinzDepartment of Nuclear Medicine, University Hospital, RWTH Aachen, 52074, Aachen, Germany.
Raphael RicharzInstitute of Radiochemistry and Experimental Molecular Imaging (IREMB), University Hospital of Cologne, 50937, Cologne, Germany.
Philipp KrapfInstitute of Radiochemistry and Experimental Molecular Imaging (IREMB), University Hospital of Cologne, 50937, Cologne, Germany.
Bernd NeumaierInstitute of Radiochemistry and Experimental Molecular Imaging (IREMB), University Hospital of Cologne, 50937, Cologne, Germany.ORCID 0000-0001-5425-3116
Boris D ZlatopolskiyInstitute of Radiochemistry and Experimental Molecular Imaging (IREMB), University Hospital of Cologne, 50937, Cologne, Germany.
Agnieszka MorgenrothDepartment of Nuclear Medicine, University Hospital, RWTH Aachen, 52074, Aachen, Germany.
RWTH Aachen University · DEUniversity Hospital Cologne · DEForschungszentrum Jülich · DEMaastricht University Medical Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The short- and long-term success of intravascular stents depends on a proper re-endothelialisation after the intervention-induced endothelial denudation. The aim of this study was to evaluate the potential of in vivo molecular imaging of glutamate carboxypeptidase II (GCPII; identical with prostate-specific membrane antigen PSMA) expression as a marker of re-endothelialisation. Fifteen Sprague Dawley rats underwent unilateral balloon angioplasty of the common carotid artery (CCA). Positron emission tomography (PET) using the GCPII-targeting tracer [

Indexed as

Angioplasty, Balloon, CoronaryGene Expression Regulation, EnzymologicPositron-Emission TomographyAnimalsCarotid Artery, CommonDisease Models, AnimalEndothelial CellsGlutamate Carboxypeptidase IIMaleRatsRats, Sprague-DawleyGlutamate Carboxypeptidase II

Identifiers

PMID29743623
PMCPMC5943322
OpenAlexW2806920589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.