Evidence map›Paper›PMID 29743573›Full record

ArticleBone marrow transplantation2018

Foxp3 expression in induced T regulatory cells derived from human umbilical cord blood vs. adult peripheral blood.

Jeong-Su Do, Fei Zhong, Alex Y Huang, Wouter J Van't Hof, Marcie Finney, Mary J Laughlin

Abstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. T cell Tolerance in Early Life.Frontiers in immunology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeong-Su DoCleveland Cord Blood Center, Cleveland, OH, USA. doj@clevelandcordblood.org.
Fei ZhongCleveland Cord Blood Center, Cleveland, OH, USA.
Alex Y HuangCase Western Reserve University, Cleveland, OH, USA.
Wouter J Van't HofCleveland Cord Blood Center, Cleveland, OH, USA.
Marcie FinneyCleveland Cord Blood Center, Cleveland, OH, USA.
Mary J LaughlinCleveland Cord Blood Center, Cleveland, OH, USA.
Cleveland Cord Blood Center · USCase Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foxp3 is essential for T regulatory cell (Treg) function. Broad complex-Tramtrack-Bric-a-brac domain (BTB) and Cap'n'collar (CNC) homology 1, transcription factor 2 (BACH2) stabilizes Treg immune homeostasis in murine studies. However, little is known regarding what role, if any, BACH2 may have in Foxp3 regulation in human-induced Treg (iTreg). We examined Foxp3 expression and regulation comparing iTreg differentiated from umbilical cord blood (UCB) vs. adult blood (AB) naive CD4

Indexed as

Cell DifferentiationFetal BloodForkhead Transcription FactorsHumansT-Lymphocytes, RegulatoryForkhead Transcription FactorsFOXP3 protein, human

Identifiers

PMID29743573
OpenAlexW2800513682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.