Evidence map›Paper›PMID 29743366›Full record

ArticleJournal of virology2018

Regulation of Virus-Associated Lymphoma Growth and Gene Expression by Bacterial Quorum-Sensing Molecules.

Jing Qiao, Yueyu Cao, Jovanny Zabaleta, Liang Yang, Lu Dai, Zhiqiang Qin

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The Role ofToxins · 2021
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Jing Qiao *Department of Pediatrics, Research Center for Translational Medicine and Key Laboratory of Arrhythmias, East Hospital, Tongji University School of Medicine, Shanghai, China.
Yueyu Cao *Department of Pediatrics, Research Center for Translational Medicine and Key Laboratory of Arrhythmias, East Hospital, Tongji University School of Medicine, Shanghai, China.
Jovanny ZabaletaDepartment of Pediatrics, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, Louisiana, USA.
Liang YangSingapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0002-2362-0128
Lu DaiDepartment of Pediatrics, Research Center for Translational Medicine and Key Laboratory of Arrhythmias, East Hospital, Tongji University School of Medicine, Shanghai, China ldai@lsuhsc.edu zqin@lsuhsc.edu.
Zhiqiang QinDepartment of Pediatrics, Research Center for Translational Medicine and Key Laboratory of Arrhythmias, East Hospital, Tongji University School of Medicine, Shanghai, China ldai@lsuhsc.edu zqin@lsuhsc.edu.
Louisiana State University · USShanghai East Hospital · CNNanyang Technological University · SG

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Translational Genomics Core (TGC)P20GM121288 · NIGMS · LSU HEALTH SCIENCES CENTER · PI Luis Del Valle · 2017 to 2026
$22.4M
Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi’s Sarcoma development in HIV+ patientsR01CA228166 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI FORREST, JAMES CRAIG, POST, STEVEN · 2018 to 2023
$1.9M
NCI NIH HHS R01 CA228166NIGMS NIH HHS P20 GM121288NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) can cause several human cancers, including primary effusion lymphoma (PEL), which frequently occur in immunocompromised patients. KSHV-infected patients often suffer from polymicrobial infections caused by opportunistic bacterial pathogens. Therefore, it is crucial to understand how these coinfecting microorganisms or their secreted metabolites may affect KSHV infection and the pathogenesis of virus-associated malignancies. Quorum sensing (QS), a cell density-based intercellular communication system, employs extracellular diffusible signaling molecules to regulate bacterial virulence mechanisms in a wide range of bacterial pathogens, such as

Indexed as

Gene Expression RegulationQuorum Sensing4-ButyrolactoneBacterial LoadHerpesviridae InfectionsHerpesvirus 8, HumanHumansLymphoma, Primary EffusionPseudomonas aeruginosaPseudomonas InfectionsQuinolonesSignal TransductionViral ProteinsVirulence2-heptyl-3-hydroxy-4-quinolone4-ButyrolactoneN-butyrylhomoserine lactoneQuinolonesViral ProteinsKSHVprimary effusion lymphomaPseudomonas aeruginosaquorum sensing

Identifiers

PMID29743366
PMCPMC6026753
OpenAlexW2799298921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.