Evidence map›Paper›PMID 29743365›Full record

ArticleJournal of virology2018

Dengue Virus Induces Increased Activity of the Complement Alternative Pathway in Infected Cells.

Sheila Cabezas, Gustavo Bracho, Amanda L Aloia, Penelope J Adamson, Claudine S Bonder, Justine R Smith, David L Gordon, Jillian M Carr

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sheila CabezasMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Gustavo BrachoMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Amanda L AloiaCell Screen SA, Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, South Australia, Australia.
Penelope J AdamsonMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Claudine S BonderCentre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.
Justine R SmithMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
David L GordonMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.
Jillian M CarrMicrobiology and Infectious Diseases and Eye & Vision Health, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia jill.carr@flinders.edu.au.ORCID https://orcid.org/0000-0002-1080-1472
Flinders University · AUSouth Australia Pathology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe dengue virus (DENV) infection is associated with overactivity of the complement alternative pathway (AP) in patient studies. Here, the molecular changes in components of the AP during DENV infection

Indexed as

Complement Pathway, AlternativeCells, CulturedComplement Factor BComplement Factor HComplement System ProteinsDengueDengue VirusEndothelium, VascularHumansRetinaComplement Factor BComplement Factor HComplement System Proteinscomplementdengue virusfactor H

Identifiers

PMID29743365
PMCPMC6026742
OpenAlexW2802673792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.