Evidence map›Paper›PMID 29743361›Full record

ArticleJournal of virology2018

Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying

Hanna B Scinto, Sandeep Gupta, Swati Thorat, Muhammad M Mukhtar, Anthony Griffiths, Jennifer Delgado, Elizabeth Plake, Hemant K Vyas, Amanda Strickland, Siddappa N Byrareddy and 16 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 9 institutions in 3 countries.

Hanna B Scinto *Texas Biomedical Research Institute, San Antonio, Texas, USA.
Sandeep Gupta *Texas Biomedical Research Institute, San Antonio, Texas, USA.
Swati Thorat *Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Muhammad M Mukhtar *Texas Biomedical Research Institute, San Antonio, Texas, USA.
Anthony GriffithsTexas Biomedical Research Institute, San Antonio, Texas, USA.
Jennifer DelgadoTexas Biomedical Research Institute, San Antonio, Texas, USA.
Elizabeth PlakeTexas Biomedical Research Institute, San Antonio, Texas, USA.
Hemant K VyasTexas Biomedical Research Institute, San Antonio, Texas, USA.
Amanda StricklandTexas Biomedical Research Institute, San Antonio, Texas, USA.
Siddappa N ByrareddyDana-Farber Cancer Institute, Boston, Massachusetts, USA.
David C MontefioriDuke University Medical Center, Durham, North Carolina, USA.
Celia LaBrancheDuke University Medical Center, Durham, North Carolina, USA.
Ranajit PalAdvanced Biosciences Laboratories Inc., Rockville, Maryland, USA.
Jim TreeceAdvanced Biosciences Laboratories Inc., Rockville, Maryland, USA.
Sharon OrndorffAdvanced Biosciences Laboratories Inc., Rockville, Maryland, USA.
Maria Grazia FerrariAdvanced Biosciences Laboratories Inc., Rockville, Maryland, USA.
Deborah WeissAdvanced Biosciences Laboratories Inc., Rockville, Maryland, USA.
Agnes-Laurence ChenineHenry M. Jackson Foundation, Bethesda, Maryland, USA.
Robert McLindenHenry M. Jackson Foundation, Bethesda, Maryland, USA.
Nelson MichaelHenry M. Jackson Foundation, Bethesda, Maryland, USA.
Jerome H KimHenry M. Jackson Foundation, Bethesda, Maryland, USA.
Merlin L RobbHenry M. Jackson Foundation, Bethesda, Maryland, USA.
Supachai Rerks-NgarmDepartment of Disease Control, Ministry of Public Health, Nonthaburi, Thailand.
Punnee PitisuttithumMahidol University, Bangkok, Thailand.
Sorachai NitayaphanArmed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
Ruth M RuprechtTexas Biomedical Research Institute, San Antonio, Texas, USA rrupecht@txbiomd.org.
Texas Biomedical Research Institute · USHenry M. Jackson Foundation · USDuke Medical Center · USJackson Foundation · USArmed Forces Research Institute of Medical Science · THDana-Farber Cancer Institute · USHarvard University · USMahidol University · THMinistry of Public Health · TH

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Humoral Correlates of Protection Against HIVR01AI100703 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI RUPRECHT, RUTH MARGRIT · 2012 to 2016
$4.0M
NIAID NIH HHS HHSN272201100023CNIAID NIH HHS R01 AI100703NIH HHS P51 OD011132NIH HHS P51 OD011133
6 · The paper itself

Abstract

The phase III RV144 human immunodeficiency virus (HIV) vaccine trial conducted in Thailand remains the only study to show efficacy in decreasing the HIV acquisition risk. In Thailand, circulating recombinant forms of HIV clade A/E (CRF01_AE) predominate; in such viruses,

Indexed as

Gene Products, envTropismAnimalsHIV-1HIV InfectionsHumansLeukocytes, MononuclearMacaca mulattaProvirusesReceptors, CCR5Simian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusThailandViral LoadViremiaVirus ReplicationGene Products, envReceptors, CCR5adaptationcoreceptor switchCRF01_AEHIVrhesus macaquesRV144 trialSHIV-E

Identifiers

PMID29743361
PMCPMC6026739
OpenAlexW2801959794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.