Evidence map›Paper›PMID 29743168›Full record

Observational studyEuropean journal of endocrinology2018

Gestational diabetes with diabetes and prediabetes risks: a large observational study.

Yun Shen, Peng Wang, Leishen Wang, Shuang Zhang, Huikun Liu, Weiqin Li, Nan Li, Wei Li, Junhong Leng, Jing Wang and 6 more

Abstract readObservational Study
In one paragraph

Observational study in European journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yun ShenPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Peng WangTianjin Women's and Children's Health Center, Tianjin, China.
Leishen WangTianjin Women's and Children's Health Center, Tianjin, China.
Shuang ZhangTianjin Women's and Children's Health Center, Tianjin, China.
Huikun LiuTianjin Women's and Children's Health Center, Tianjin, China.
Weiqin LiTianjin Women's and Children's Health Center, Tianjin, China.
Nan LiTianjin Women's and Children's Health Center, Tianjin, China.
Wei LiTianjin Women's and Children's Health Center, Tianjin, China.
Junhong LengTianjin Women's and Children's Health Center, Tianjin, China.
Jing WangTianjin Women's and Children's Health Center, Tianjin, China.
Huiguang TianTianjin Women's and Children's Health Center, Tianjin, China.
Cuilin ZhangDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Jaakko TuomilehtoDasman Diabetes Institute, Dasman, Kuwait.
Xilin YangDepartment of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin, China.
Zhijie YuPopulation Cancer Research program, Dalhousie University, Halifax, Nova Scotia, Canada.
Gang HuPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
NIDDK NIH HHS R01 DK100790NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

aimsTo compare risks of early postpartum diabetes and prediabetes in Chinese women with and without gestational diabetes mellitus (GDM) during pregnancy. SUBJECTS AND

methodsTianjin GDM observational study included 1263 women with a history of GDM and 705 women without GDM who participated in the urban GDM universal screening survey by using World Health Organization's criteria. Postpartum diabetes and prediabetes were identified after a standard oral glucose tolerance test. Cox proportional hazards regression was used to assess risks of postpartum diabetes and prediabetes between women with and without GDM.

resultsDuring a mean follow-up of 3.53 years postpartum, 90 incident cases of diabetes and 599 incident cases of prediabetes were identified. Multivariable-adjusted hazard ratios among women with prior GDM, compared with those without it, were 76.1 (95% CI: 23.6-246) for diabetes and 25.4 (95% CI: 18.2-35.3) for prediabetes. When the mean follow-up extended to 4.40 years, 121 diabetes and 616 prediabetes cases were identified. Women with prior GDM had a 13.0-fold multivariable-adjusted risk (95% CI: 5.54-30.6) for diabetes and 2.15-fold risk (95% CI: 1.76-2.62) for prediabetes compared with women without GDM. The positive associations between GDM and the risks of postpartum diabetes and prediabetes were significant and persistent when stratified by younger and older than 30 years at delivery and normal weight and overweight participants.

conclusionsThe present study indicated that women with prior GDM had significantly increased risks for postpartum diabetes and prediabetes, with the highest risk at the first 3-4 years after delivery, compared with those without GDM.

Indexed as

Postpartum PeriodAdultChinaDiabetes, GestationalDiabetes Mellitus, Type 2FemaleGlucose Tolerance TestHumansPrediabetic StatePregnancyRisk Factors

Identifiers

PMID29743168
PMCPMC6009844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.