ArticleEpidemiology and infection2018
Significant spike in excess mortality in England in winter 2014/15 - influenza the likely culprit.
Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- High Clinical Burden of Influenza Disease in Adults Aged ≥ 65 Years: Can We Do Better? A Systematic Literature Review.Advances in therapy · 2023Pooled it
- Changes in Healthcare Utilization in Japan in the Aftermath of the COVID-19 Pandemic: A Time Series Analysis of Japanese National Data Through November 2023.Healthcare (Basel, Switzerland) · 2024Article
- Postpandemic Sentinel Surveillance of Respiratory Diseases in the Context of the World Health Organization Mosaic Framework: Protocol for a Development and Evaluation Study Involving the English Primary Care Network 2023-2024.JMIR public health and surveillance · 2024Article
- Influenza: cause or excuse? An analysis of flu's influence on worsening mortality trends in England and Wales, 2010-19.British medical bulletin · 2024Article
- Assessing the impact of energy and fuel poverty on health: a European scoping review.European journal of public health · 2023Article
- Mortality associated with Omicron and influenza infections in France before and during the COVID-19 pandemic.Epidemiology and infection · 2023Article
- Impact of General Practitioner Education on Acceptance of an Adjuvanted Seasonal Influenza Vaccine among Older Adults in England.Behavioral sciences (Basel, Switzerland) · 2023Article
- An intercountry comparison of the impact of the paediatric live attenuated influenza vaccine (LAIV) programme across the UK and the Republic of Ireland (ROI), 2010 to 2017.Influenza and other respiratory viruses · 2023Article
- Excess mortality in the first COVID pandemic peak: cross-sectional analyses of the impact of age, sex, ethnicity, household size, and long-term conditions in people of known SARS-CoV-2 status in England.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Article
- Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013-2018).BMC public health · 2020Article
- Spatio-temporal model to estimate life expectancy and to detect unusual trends at the local authority level in England.BMJ open · 2020Article
- Article
- All-cause excess mortality observed by age group and regions in the first wave of the COVID-19 pandemic in England.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
- Influenza vaccines: the potential benefits of cell-culture isolation and manufacturing.Therapeutic advances in vaccines and immunotherapy · 2020Review
- Recent adverse mortality trends in Scotland: comparison with other high-income countries.BMJ open · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significant increases in excess all-cause mortality, particularly in the elderly, were observed during the winter of 2014/15 in England. With influenza A(H3N2) the dominant circulating influenza A subtype, this paper determines the contribution of influenza to this excess controlling for weather. A standardised multivariable Poisson regression model was employed with weekly all-cause deaths the dependent variable for the period 2008-2015. Adjusting for extreme temperature, a total of 26 542 (95% CI 25 301-27 804) deaths in 65+ and 1942 (95% CI 1834-2052) in 15-64-year-olds were associated with influenza from week 40, 2014 to week 20, 2015. This is compatible with the circulation of influenza A(H3N2). It is the largest estimated number of influenza-related deaths in England since prior to 2008/09. The findings highlight the potential health impact of influenza and the important role of the annual influenza vaccination programme that is required to protect the population including the elderly, who are vulnerable to a severe outcome.
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