Evidence map›Paper›PMID 29743121›Full record

ArticleCritical care (London, England)2018

High-frequency oscillatory ventilation guided by transpulmonary pressure in acute respiratory syndrome: an experimental study in pigs.

Philipp Klapsing, Onnen Moerer, Christoph Wende, Peter Herrmann, Michael Quintel, Annalen Bleckmann, Jan Florian Heuer

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Philipp KlapsingDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.
Onnen MoererDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.
Christoph WendeDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.
Peter HerrmannDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.
Michael QuintelDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany.
Annalen BleckmannDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Jan Florian HeuerDepartment of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Management, University Medical Center Göttingen, Göttingen, Germany. j.heuer@augusta-bochum.de.
Universitätsmedizin Göttingen · DEAugusta-Kranken-Anstalt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent clinical studies have not shown an overall benefit of high-frequency oscillatory ventilation (HFOV), possibly due to injurious or non-individualized HFOV settings. We compared conventional HFOV (HFOV

methodsARDS was induced in eight pigs by intrabronchial installation of hydrochloric acid (0.1 N, pH 1.1; 2.5 ml/kg body weight). The animals were initially ventilated in volume-controlled mode with low tidal volumes (6 ml kg

resultsCardiac output, stroke volume, mean arterial pressure and intrathoracic blood volume index were significantly higher during HFOV P

conclusionHFOV P

Indexed as

PressureAnimalsArterial PressureBlood Volume DeterminationCardiac OutputHigh-Frequency VentilationLungMonitoring, PhysiologicPositive-Pressure RespirationPulmonary Gas ExchangeRespiratory Distress SyndromeStroke VolumeSwineAerated lung tissueHemodynamicsHFOVOxygenationTranspulmonary pressureVolume controlled ventilation

Identifiers

PMID29743121
PMCPMC5943989
OpenAlexW2799845343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.