ArticleCritical care (London, England)2018
Feasibility and safety of low-flow extracorporeal CO
Article in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 54 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Extracorporeal CO2 Removal (ECCO2R) With a Renal Replacement Platform (PRISMALUNG) to Enhance Lung Protective Ventilation in Patients With Mild to Moderate Acute Respiratory Distress Syndrome (ARDS)
Low-flow Extracorporeal Carbon Dioxide Removal Using a Renal Replacement Therapy Platform for Correction of Hypercapnia in COVID-19-associated Acute Respiratory Distress Syndrome
Safety and Efficacy of Low-Flow ECMO in a Multi-modal Cohort of Adults in Respiratory Failure
Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of extracorporeal carbon dioxide removal in facilitating ultra-protective ventilation strategies for patients with acute respiratory distress syndrome: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Effects of extracorporeal COCritical care (London, England) · 2024Pooled it
- The evolution of ECCO₂R: rethinking pump selection.Critical care (London, England) · 2026Article
- The Evolving Role of Extracorporeal Carbon Dioxide Removal in Acute Respiratory Failure: A Narrative Review.Cureus · 2026Review
- Extracorporeal Carbon Dioxide Removal in Acute Respiratory Distress Syndrome: Physiologic Rationale and Phenotype-Based Perspectives.Medicina (Kaunas, Lithuania) · 2026Review
- A prospective clinical evaluation of new ECCO2R technology in mild to moderate ARDS patients: assessing ultra-lung-protective ventilation with PRISMALUNG.Critical care (London, England) · 2026Article
- Case Report: Electrical impedance tomography-guided ultra-protective lung ventilation during veno-venous extracorporeal membrane oxygenation support for fat embolism syndrome complicated by severe acute respiratory distress syndrome.Frontiers in medicine · 2026Article
- Evolution of extracorporeal membrane oxygenation: historical milestones and advanced developments.The journal of extra-corporeal technology · 2025Review
- Effect of low bicarbonate substitution solution on COIntensive care medicine experimental · 2025Article
- Sensing molecular carbon dioxide: a translational focus for respiratory disease.Physiological reviews · 2025Review
- The role of extracorporeal COFrontiers in medicine · 2025Review
- Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal.Journal of clinical medicine · 2024Review
- Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future.World journal of critical care medicine · 2024Article
- Lung (extracorporeal COJournal of anesthesia, analgesia and critical care · 2024Article
- Combined Use of Alkaline Agents With Low-Flow Extracorporeal Carbon Dioxide Removal in Carbon Dioxide Inhalation Models Preserving Inspiratory Efforts.Journal of acute medicine · 2024Article
- Low-flow ECCOHeliyon · 2024Article
- Mapping a Decade (2014-2024) of Research on Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Visual Analysis with CiteSpace and VOSviewer.Journal of multidisciplinary healthcare · 2024Article
- Current knowledge gaps in extracorporeal respiratory support.Intensive care medicine experimental · 2023Review
- Safety and Effectiveness of Carbon Dioxide Removal CO2RESET Device in Critically Ill Patients.Membranes · 2023Article
- Ultraprotective Ventilation via ECCO2R in Three Patients Presenting an Air Leak: Is ECCO2R Effective?Journal of personalized medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtracorporeal carbon-dioxide removal (ECCO
methodsTwenty patients with mild (n = 8) or moderate (n = 12) ARDS were included. VT was gradually lowered from 6 to 5, 4.5, and 4 ml/kg, and PEEP adjusted to reach 23 ≤ P
resultsWhile VT was reduced from 6 to 4 ml/kg and P
conclusionsA low-flow ECCO
trial registrationClinicalTrials.gov, NCT02606240. Registered on 17 November 2015.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.