ArticleBMC pregnancy and childbirth2018
The effect of pre-pregnancy hair dye exposure on infant birth weight: a nested case-control study.
Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Hair Dyes in Pregnancy: A Systematic Review and Meta-Analysis.Journal of pregnancy · 2026Pooled it
- Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort.Environment international · 2025Article
- Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing.Chemical research in toxicology · 2022Review
- Personal care products: Demographic characteristics and maternal hormones in pregnant women from Puerto Rico.Environmental research · 2022Article
- Endocrine disrupting chemical-associated hair product use during pregnancy and gestational age at delivery: a pilot study.Environmental health : a global access science source · 2021Article
- Chemical/straightening and other hair product usage during childhood, adolescence, and adulthood among African-American women: potential implications for health.Journal of exposure science & environmental epidemiology · 2020Article
- The associations between maternal lifestyles and antenatal stress and anxiety in Chinese pregnant women: A cross-sectional study.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundLimited evidences were reported about the risk of pre-pregnancy hair dye use or irregular menstruation with abnormal birth weight during pregnancy, and their joint effects were also unknown. The aim of our study was to explore whether the pre-pregnancy exposure of hair dye and irregular menstruation were associated with the risk of abnormal birth weight.
methodsWe conducted a nested case-control study from a prospective cohort of 6203 pregnant women. Low birth weight study included 315 mother-infant pairs (105 LBW cases and 210 matched controls), and macrosomia study included 381 mother-infant pairs (127 macrosomia cases and 254 matched controls). Meanwhile, lifestyle information including hair dying custom and menstrual history were collected by face-to-face questionnaires and birth outcomes were extracted from the medical records. The logistic regressions models were used to analyze the join effect of irregular menstruation and hair dye use.
resultsPre-pregnancy hair dye use was associated with increased risk of LBW (adjusted OR = 1.71, 95% CI: 1.01-2.92, P = 0.048). Irregular menstruation had high risk of LBW (adjusted OR = 2.79, 95% CI: 1.53-5.09, P = 0.001) and macrosomia (adjusted OR = 1.93, 95% CI: 1.09-3.44, P = 0.023). Additionally, in the LBW study, women who used hair dye with pre-pregnancy BMI < 18.5 kg/m
conclusionOur study showed that either pre-pregnancy hair dye use or irregular menstruation was associated with abnormal birth weight, especially, their joint effects could furthermore increase the risk of low birth weight infants when these two factors existed simultaneously.
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