ArticleChronic respiratory disease
Depression is a major determinant of both disease-specific and generic health-related quality of life in people with severe COPD.
Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2019Pooled it
- Depression and anxiety disorders in chronic obstructive pulmonary disease patients: Prevalence, disease impact, treatment.World journal of psychiatry · 2024Review
- An Applicable Framework for Understanding Successful Aging of People Living with HIV and Comorbid Chronic Obstructive Pulmonary Disease.Nursing (Auckland, N.Z.) · 2024Article
- The Relationship Between Benefit Finding and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease: The Mediating Effects of Self-Management.International journal of chronic obstructive pulmonary disease · 2024Article
- Synergistic Impact of the Symptom Cluster on Health-Related Quality of Life in Patients With Chronic Obstructive Pulmonary Disease: A Secondary Data Analysis.Clinical nursing research · 2022Article
- Age, Cognitive Factors, and Acceptance of Living with the Disease in Rheumatoid Arthritis: The Short-Term Perspective.International journal of environmental research and public health · 2022Article
- Fate or coincidence: do COPD and major depression share genetic risk factors?Human molecular genetics · 2021Article
- Comorbid Anxiety and Depression, Though Underdiagnosed, Are Not Associated with High Rates of Low-Value Care in Patients with Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2021Article
- Health related quality of life in chronic kidney disease; a descriptive study in a rural Sri Lankan community affected by chronic kidney disease.Health and quality of life outcomes · 2020Article
- Loneliness and ED Visits in Chronic Obstructive Pulmonary Disease.Mayo Clinic proceedings. Innovations, quality & outcomes · 2019Article
- Psychological burden associated with worse clinical outcomes in sarcoidosis.BMJ open respiratory research · 2019Article
- Symptomatology and Quality of Life of Older People With HIV and Comorbid Chronic Obstructive Pulmonary Diseases From an HIV Clinic in Birmingham, Alabama.The Journal of the Association of Nurses in AIDS Care : JANACArticle
- Healthcare professionals' representation toward optimal palliative care provision for COPD patients: a cross-sectional survey.Therapeutic advances in respiratory diseaseArticle
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The quality of life of patients with chronic obstructive pulmonary disease (COPD) decreases significantly as the disease progresses; those with severe COPD are affected most. This article investigates predictors of the disease-specific and generic health-related quality of life (HRQL) in patients with severe COPD. This multicentre prospective cross-sectional study enrolled 80 patients with severe COPD. At enrolment, all patients completed a disease-specific instrument, the St George's Respiratory Questionnaire (SGRQ), and a generic instrument, the Short Form 36 Health Survey Questionnaire (SF-36). The data were analyzed by Pearson's correlation and multiple linear regression. The mean age of the patients was 66 ± 8 years; 93% were males. The SGRQ and SF-36 scores were not influenced by age or sex. Depression, dyspnea, the number of exacerbations, and exercise capacity significantly predicted the total SGRQ score ( p < 0.05). Depression was the strongest determinant of the total SGRQ score. The SF-36 physical component summary scores were related to depression, dyspnea, and the number of exacerbations ( p < 0.05). In comparison, the SF-36 mental component summary scores were related to depression and anxiety ( p < 0.05). Depression is a significant determinant of both the disease-specific and generic HRQL in patients with severe COPD. Screening and early intervention for depression in patients with severe COPD could improve the HRQL.
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