Observational studyMedicine2018
Earlier surgery improves outcomes from painful chronic pancreatitis.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A meta-analysis of the long-term outcomes following surgery or endoscopic therapy for chronic pancreatitis.Langenbeck's archives of surgery · 2022Pooled it
- Risk factors for exocrine pancreatic insufficiency after pancreatic surgery: a systematic review and meta-analysis.Canadian journal of surgery. Journal canadien de chirurgiePooled it
- Trial
- A Comparative Study on Quality of Life Between Primary Early Surgery and Late Surgery in Chronic Calcific Pancreatitis using the SF-36 Questionnaire-A Prospective Observational Cohort Study.Digestive diseases and sciences · 2026Observational
- Article
- Current status of total pancreatectomy with islet autotransplantation for chronic and recurrent acute pancreatitis.Annals of gastroenterological surgery · 2024Review
- Recent advances in the understanding and management of chronic pancreatitis pain.Journal of pancreatology · 2024Review
- Surgical Interventions in Chronic Pancreatitis: A Systematic Review of Their Impact on Quality of Life.Cureus · 2024Review
- Quality of life after total pancreatectomy with islet autotransplantation for chronic pancreatitis in Japan.Islets · 2023Article
- Frey procedure for chronic pancreatitis: A narrative review.Annals of medicine and surgery (2012) · 2022Review
- Surgical Outcomes and Trends for Chronic Pancreatitis: An Observational Cohort Study from a High-Volume Centre.Journal of clinical medicine · 2022Article
- Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results.World journal of clinical cases · 2021Article
- A Network Meta-analysis of Surgery for Chronic Pancreatitis: Impact on Pain and Quality of Life.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Review
- Frey's plus versus Frey's procedure for chronic pancreatitis: Analysis of postoperative outcomes and quality of life.Annals of hepato-biliary-pancreatic surgery · 2020Article
- Turkish Gastroenterology Association, Pancreas Study Group, Chronic Pancreatitis Committee Consensus Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Disease duration before surgical resection for chronic pancreatitis impacts long-term outcome.Medicine · 2020Article
- Impact of prior interventional treatment on the complications after Frey procedure for chronic pancreatitis.Langenbeck's archives of surgery · 2019Article
- Early outcome of Frey's procedure for chronic pancreatitis: Nepalese tertiary center experience.BMC surgery · 2019Article
- Article
- Surgery in Chronic Pancreatitis: Indication, Timing and Procedures.Visceral medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The timing of surgery for painful chronic pancreatitis (CP) may affect outcomes.Clinical course, Izbicki pain scores, and pancreatic function were retrospectively compared and analyzed between patients undergoing either early or late surgery (< 3 or ≥ 3 years from diagnosis) for painful CP in a single center from 2007 to 2012.The early surgery group (n = 98) more frequently than the late group (n = 199) had abdominal pain with jaundice (22.4% vs 9.5%, P = .002) and pancreatic mass +/- ductal dilatation (47% vs 27%, P < .001), but less frequently abdominal pain alone (73.5% vs 85.9%, P = .009), ductal dilatation alone (31% vs 71%, P < .001), parenchymal calcification (91.8% vs 100%, P < .001) or exocrine insufficiency (60% vs 72%, P = .034); there were no other significant differences. The early group had longer hospital stay (14.4 vs 12.2 days, P = .009), but no difference in complications. Significantly greater pain relief followed early surgery (complete 69% vs 47%, partial 22% vs 37%, none 8% vs 16%, P = .01) with lower rates of exocrine (60% vs 80%, P = .005) and endocrine insufficiency (36% vs 53%, P = .033).Our data indicate that early surgery results in higher rates of pain relief and pancreatic sufficiency than late surgery for chronic pancreatitis patients. Frey and Berne procedures showed better results than other surgical procedures.
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