Observational studyMedicine2018
Characteristics and management of pyogenic liver abscess: A European experience.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
94 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.
- Clinical characteristics, diagnosis, treatment, and outcome of patients with liver abscess due to Aspergillus spp: a systematic review of published cases.BMC infectious diseases · 2024Pooled it
- Efficacy of empirical Ciprofloxacin or Cefixime plus Metronidazole therapy for the treatment of liver abscess: a randomized control clinical trial.Scientific reports · 2024Trial
- Clinical efficacy of ulinastatin in the treatment of unliquefied pyogenic liver abscess complicated by septic shock: A randomized controlled trial.Immunity, inflammation and disease · 2023Trial
- Isolated left-lobe metastatic hepatic abscess due to portal pyemia from microperforated ascending colon carcinoma: a rare case report.International journal of surgery case reports · 2026Article
- Culture-Negative Pyogenic Liver Abscess Presenting as Lung Abscess and Empyema Through Transdiaphragmatic Spread.Respirology case reports · 2026Article
- Bacterial versus parasitic liver abscesses in children: a retrospective cohort study of clinical and laboratory differences.BMC pediatrics · 2026Article
- Article
- When Clinical Improvement Does Not Reflect Radiological Response: A Culture-Negative Giant Pyogenic Liver Abscess.Healthcare (Basel, Switzerland) · 2026Article
- Odontogenic liver abscess in one patient.World journal of emergency medicine · 2026Article
- Article
- Article
- Liver abscesses in Southern Europe: clinical and microbiological characterization of a retrospective cohort.BMC infectious diseases · 2026Observational
- Giant pyogenic ruptured hepatic abscess causing intestinal occlusion resolved by a laparoscopic approach: a case report.Journal of surgical case reports · 2026Article
- The 3D landscape of infection: spatial organization andFrontiers in immunology · 2026Review
- Article
- Clinical characteristics and etiological analysis in liver abscess: a retrospective study.Frontiers in cellular and infection microbiology · 2026Article
- Pyogenic liver abscess in the North Denmark Region - a population-based cohort study (2010-2022).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Iron Metabolism Disorders Associated With the Severity of Pyogenic Liver Abscess.Food science & nutrition · 2025Article
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- Predictive factors for liver abscess liquefaction degree based on clinical, laboratory, and computed tomography data.World journal of gastrointestinal surgery · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyogenic liver abscess (PLA) are space-occupying lesions in the liver associated with high morbidity and mortality. The aim of this study is to review an Italian hospital experience in epidemiological, clinical patterns, and management of PLA.We performed a retrospective, descriptive case series at a single center assessing demographic characteristics, presentation patterns, etiological factors, microbiological etiology, and management for patients treated for PLA between 2000 and 2016.Around 109 patients were identified. The majority of patients presented with fever (73%); right upper abdominal pain in 63.3%, vomiting and nausea in 28.4%. The most common laboratory abnormality among included items was increased C-reactive protein and fibrinogen blood levels, respectively, in 98% and 93.9% of cases. Abdominal ultrasound was the diagnostic investigation in 42.4% of cases; CT scan and MR imaging were performed in 51.1% and 3.3% of cases respectively. We observed blood or pus culture study in 99 cases of which only 53.5% came with positive microbial reports. The most common organism identified was Escherichia coli (26.5%), followed by Streptococcus spp (13.2%). Early antibiotic treatment started on all patients and 66.7% of cases required different approaches, Ultrasound or CT-guided needle aspiration of PLA was performed in 13 patients (11%) and percutaneous abscess drainage was performed on 72 patients (67%).PLA is a diagnostically challenging problem due to nonspecific presenting characteristics. The microbiological yield identified was a typical European spectrum with a preponderance of Escherichia coli infections. Once recognized, percutaneous drainage and antibiotic treatment are the mainstay of management for PLA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.