ArticleCell reports2018
Hippocampal Network Dynamics during Rearing Episodes.
Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of the Effects of Capsaicin on Alzheimer's Disease.International journal of molecular sciences · 2023Pooled it
- Place and behavioral modulation of hippocampal neurons during immobility.Nature communications · 2026Article
- Rearing and Head Scanning as Functionally Equivalent Information-Seeking Behaviors.bioRxiv : the preprint server for biology · 2026Article
- In Vivo Analysis of Medial Perforant Path-Evoked Excitation and Inhibition in Dentate Granule Cells.eNeuro · 2025Article
- Rearing Behavior as Indicator of Spatial Novelty and Memory in Developing Rats.The European journal of neuroscience · 2025Article
- Curiosity shapes spatial exploration and cognitive map formation in humans.Communications psychology · 2024Article
- Exploratory Rearing Is Governed by Hypothalamic Melanin-Concentrating Hormone Neurons According to Locus Ceruleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Working memory features are embedded in hippocampal place fields.Cell reports · 2024Article
- HeterozygousHeliyon · 2024Article
- Hippocampal inactivation during rearing on hind legs impairs spatial memory.Scientific reports · 2023Article
- Specific behaviors during auditory fear conditioning and postsynaptic expression of AMPA receptors in the basolateral amygdala predict interindividual differences in fear generalization in male rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Depression-AssociatedBrain sciences · 2022Article
- Moderate effect of early-life experience on dentate gyrus function.Molecular brain · 2022Article
- Medial orbitofrontal cortex and nucleus accumbens mediation in risk assessment behaviors in adolescents and adults.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Two distinct ways to form long-term object recognition memory during sleep and wakefulness.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Action-driven remapping of hippocampal neuronal populations in jumping rats.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Disarranged neuroplastin environment upon aging and chronic stress recovery in female Sprague Dawley rats.The European journal of neuroscience · 2022Article
- Locomotor and histological changes in a cuprizone-induced animal model of multiple sclerosis: comparison between alpha-tocopherol and fingolimod.Research in pharmaceutical sciences · 2022Article
- Temporal dynamics of cholinergic activity in the septo-hippocampal system.Frontiers in neural circuits · 2022Article
- Frequency matters: how changes in hippocampal theta frequency can influence temporal coding, anxiety-reduction, and memory.Frontiers in systems neuroscience · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Animals build a model of their surroundings on the basis of information gathered during exploration. Rearing on the hindlimbs changes the vantage point of the animal, increasing the sampled area of the environment. This environmental knowledge is suggested to be integrated into a cognitive map stored by the hippocampus. Previous studies have found that damage to the hippocampus impairs rearing. Here, we characterize the operational state of the hippocampus during rearing episodes. We observe an increase of theta frequency paralleled by a sink in the dentate gyrus and a prominent theta-modulated fast gamma transient in the middle molecular layer. On the descending phase of rearing, a decrease of theta power is detected. Place cells stop firing during rearing, while a different subset of putative pyramidal cells is activated. Our results suggest that the hippocampus switches to a different operational state during rearing, possibly to update spatial representation with information from distant sources.
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