ArticleRevista Brasileira de terapia intensiva2018
SOFA in the first 24 hours as an outcome predictor of acute liver failure.
Article in Revista Brasileira de terapia intensiva, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Progress on clinical prognosis assessment in liver failure.Liver research (Beijing, China) · 2023Review
- Association between thrombomodulin and high mobility group box 1 in sepsis patients.World journal of critical care medicine · 2020Article
- Acute-On-Chronic Liver Failure: The Role of Prognostic Scores in a Single-Center Experience.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Day-1 PELOD-2 and day-1 "quick" PELOD-2 scores in children with sepsis in the PICU.Jornal de pediatriaArticle
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3 authors.
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Abstract
objectiveTo describe a cohort of patients with acute liver failure and to analyze the demographic and clinical factors associated with mortality.
methodsRetrospective cohort study in which all patients admitted for acute liver failure from July 28, 2012, to August 31, 2017, were included. Clinical and demographic data were collected using the Epimed System. The SAPS 3, SOFA, and MELD scores were measured. The odds ratios and 95% confidence intervals were estimated. Receiver operating characteristics curves were obtained for the prognostic scores, along with the Kaplan-Meier survival curve for the score best predicting mortality.
resultsThe majority of the 40 patients were female (77.5%), and the most frequent etiology was hepatitis B (n = 13). Only 35% of the patients underwent liver transplantation. The in-hospital mortality rate was 57.5% (95%CI: 41.5 - 73.5). Among the scores investigated, only SOFA remained associated with risk of death (OR = 1.37; 95%CI 1.11 - 1.69; p < 0.001). After SOFA stratification into < 12 and ≥ 12 points, survival was higher in patients with SOFA <12 (log-rank p < 0.001).
conclusionSOFA score in the first 24 hours was the best predictor of fatal outcome.
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