ArticleMemorias do Instituto Oswaldo Cruz2018
Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?
Article in Memorias do Instituto Oswaldo Cruz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 42 citations in OpenAlex.
- Detection of Trypanosoma cruzi-infected triatomines in Iquitos: possible incipient colonisation in the largest metropolis of the Peruvian Amazon.Memorias do Instituto Oswaldo Cruz · 2026Article
- Epidemiology of Acute Chagas Disease in the Amazon: Association between the açaí production chain and case reports in Pará state, Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- On the juice? Trypanosoma cruzi vectorial-oral outbreak investigation in a semi-arid rural area of Brazil.Parasites & vectors · 2025Article
- Chagas disease in Trinidad and Tobago - a call to action.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- Cardiovascular outcomes of chagas-induced non-ischemic cardiomyopathy versus other nonischemic cardiomyopathies: a regression matched national cohort analysis.American journal of cardiovascular disease · 2025Article
- Rhodnius (Stål, 1859) (Hemiptera, Triatominae) genus in Bolivian Amazonia: a risk for human populations?Parasites & vectors · 2022Article
- Immature instars of three species of Rhodnius Stål, 1859 (Hemiptera, Reduviidae, Triatominae): morphology, morphometry, and taxonomic implications.Parasites & vectors · 2022Article
- Chagas disease control-surveillance in the Americas: the multinational initiatives and the practical impossibility of interrupting vector-borne Trypanosoma cruzi transmission.Memorias do Instituto Oswaldo Cruz · 2022Article
- Chagas disease in the context of the 2030 agenda: global warming and vectors.Memorias do Instituto Oswaldo Cruz · 2022Article
- Chagas disease (American trypanosomiasis) in the context of the 2030 agenda. Insights into global warming and vector control.Memorias do Instituto Oswaldo Cruz · 2022Article
- Chagas heart disease: An overview of diagnosis, manifestations, treatment, and care.World journal of cardiology · 2021Review
- Predictors of development of cardiac and digestive disorders among patients with indeterminate chronic Chagas Disease.PLoS neglected tropical diseases · 2021Article
- PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile.Communications biology · 2021Article
- Deforestation effects on Attalea palms and their resident Rhodnius, vectors of Chagas disease, in eastern Amazonia.PloS one · 2021Article
- Shared neuroimmune and oxidative pathways underpinning Chagas disease and major depressive disorder.Translational psychiatry · 2020Review
- Progression Rate from the Indeterminate Form to the Cardiac Form in Patients with Chronic Chagas Disease: Twenty-Two-Year Follow-Up in a Brazilian Urban Cohort.Tropical medicine and infectious disease · 2020Article
- Fatal acute Chagas disease by Trypanosoma cruzi DTU TcI, Ecuador.BMC infectious diseases · 2020Article
- Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon).Memorias do Instituto Oswaldo Cruz · 2020Article
- Landmarks of the Knowledge andFrontiers in cellular and infection microbiology · 2020Review
- Epidemiological profile of acute Chagas disease in individuals infected by oral transmission in northern Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Diseases Information System (SINAN) were evaluated. During this period, 2,030 of the 16,807 reported cases were confirmed, with a higher incidence between the months of August and December, thus characterising a seasonal pattern of acute infection, and coinciding with the higher production of "açaí", one fruit likely involved in the oral transmission of the disease. Evaluation of the absolute numbers of confirmed ACD cases secondary to oral infection suggests that infection through this route increased during the 2010-2016 period, differing from what was recorded in terms of vectorial or other infection routes. These findings point to the need of intensifying strategies to prevent or substantially reduce oral transmission.
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