Evidence map›Paper›PMID 29741589›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

C-Reactive Protein Response in Patients With Post-Treatment Lyme Disease Symptoms Versus Those With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Melanie Uhde, Alyssa Indart, Brian A Fallon, Gary P Wormser, Adriana R Marques, Suzanne D Vernon, Armin Alaedini

Abstract readComparative StudyLetter
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Neuropsychiatric Symptoms and Tick-Borne Diseases.Current topics in behavioral neurosciences · 2023
    Article
  7. Metabolic Response in Patients With Post-treatment Lyme Disease Symptoms/Syndrome.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  8. Lyme Disease in Humans.Current issues in molecular biology · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melanie UhdeDepartment of Medicine, Columbia University Medical Center, New York.
Alyssa IndartDepartment of Medicine, Columbia University Medical Center, New York.
Brian A FallonDepartment of Psychiatry, Columbia University Medical Center, New York.
Gary P WormserDivision of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla.
Adriana R MarquesLaboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Suzanne D VernonBateman Horne Center, Salt Lake City, Utah.
Armin AlaediniDepartment of Medicine, Columbia University Medical Center, New York.

Funding

Assessment Of Patients With Borrelia InfectionZIAAI000695 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARQUES, ADRIANA R · 2009 to 2025
$8.8M
Intestinal Immune Response in Myalgic Encephalomyelitis/Chronic Fatigue SyndromeR21AI121996 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALAEDINI, ARMIN · 2016 to 2017
$440k
NIAID NIH HHS R21 AI121996
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultArthralgiaCase-Control StudiesCohort StudiesC-Reactive ProteinFatigueFatigue Syndrome, ChronicFemaleHumansMiddle AgedPost-Lyme Disease SyndromeSurveys and QuestionnairesC-Reactive Protein

Identifiers

PMID29741589
PMCPMC6160605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.