Evidence map›Paper›PMID 29740788›Full record

ArticleJournal of general internal medicine2019

Behavioral Economics Interventions to Improve Outpatient Antibiotic Prescribing for Acute Respiratory Infections: a Cost-Effectiveness Analysis.

Cynthia L Gong, Kenneth M Zangwill, Joel W Hay, Daniella Meeker, Jason N Doctor

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Brief Educational Intervention to Increase ED Initiation of Buprenorphine for Opioid Use Disorder (OUD).Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2022
    Trial
  3. Estimating cost savings from reducing antibiotic overprescription in european general practices.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cynthia L GongUniversity of Southern California Leonard D. Schaeffer Center for Health Policy & Economics, Los Angeles, CA, USA. gongc@usc.edu.
Kenneth M ZangwillLos Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Los Angeles, CA, USA.
Joel W HayUniversity of Southern California Leonard D. Schaeffer Center for Health Policy & Economics, Los Angeles, CA, USA.
Daniella MeekerUniversity of Southern California Leonard D. Schaeffer Center for Health Policy & Economics, Los Angeles, CA, USA.
Jason N DoctorUniversity of Southern California Leonard D. Schaeffer Center for Health Policy & Economics, Los Angeles, CA, USA.

Funding

Use of Behavioral Economics to Improve Treatment of Acute Respiratory InfectionsRC4AG039115 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DOCTOR, JASON N. · 2010 to 2010
$11.5M
SCANNER: Scalable National Network for Effectiveness ResearchR01HS019913 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OHNO-MACHADO, LUCILA · 2010 to 2010
$8.3M
AHRQ HHS R01 HS019913ARRA NIH HHSNIA NIH HHS RC4 AG039115
6 · The paper itself

Abstract

backgroundBehavioral economics interventions have been shown to effectively reduce the rates of inappropriate antibiotic prescriptions for acute respiratory infections (ARIs).

objectiveTo determine the cost-effectiveness of three behavioral economic interventions designed to reduce inappropriate antibiotic prescriptions for ARIs.

designThirty-year Markov model from the US societal perspective with inputs derived from the literature and CDC surveillance data. SUBJECTS: Forty-five-year-old adults with signs and symptoms of ARI presenting to a healthcare provider.

interventions(1) Provider education on guidelines for the appropriate treatment of ARIs; (2) Suggested Alternatives, which utilizes computerized clinical decision support to suggest non-antibiotic treatment choices in lieu of antibiotics; (3) Accountable Justification, which mandates free-text justification into the patient's electronic health record when antibiotics are prescribed; and (4) Peer Comparison, which sends a periodic email to prescribers about his/her rate of inappropriate antibiotic prescribing relative to clinician colleagues. MAIN MEASURES: Discounted costs, quality-adjusted life years (QALYs), and incremental cost-effectiveness ratios. KEY

resultsEach intervention has lower costs but higher QALYs compared to provider education. Total costs for each intervention were $178.21, $173.22, $172.82, and $172.52, and total QALYs were 14.68, 14.73, 14.74, and 14.74 for the control, Suggested Alternatives, Accountable Justification, and Peer Comparison groups, respectively. Results were most sensitive to the quality-of-life of the uninfected state, and the likelihood and costs for antibiotic-associated adverse events.

conclusionsBehavioral economics interventions can be cost-effective strategies for reducing inappropriate antibiotic prescriptions by reducing healthcare resource utilization.

Indexed as

AdultBehavior TherapyCase-Control StudiesClinical Decision-MakingCost-Benefit AnalysisHumansInappropriate PrescribingMarkov ChainsMiddle AgedPractice Patterns, Physicians'Quality-Adjusted Life YearsRespiratory Tract InfectionsYoung Adultcost-effectivenesshealthcare administrationinfectious diseasephysician behavior

Identifiers

PMID29740788
PMCPMC6544688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.