Evidence map›Paper›PMID 29740785›Full record

ArticleMolecular biology reports2018

Regulation of myostatin expression is associated with growth and muscle development in commercial broiler and DMC muscle.

Tengfei Dou, Zhengtian Li, Kun Wang, Lixian Liu, Hua Rong, Zhiqiang Xu, Ying Huang, Dahai Gu, Xiaobo Chen, Wenyuan Hu and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular biology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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  9. Effects ofFrontiers in veterinary science · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 3 countries.

Tengfei DouYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Zhengtian LiYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Kun WangYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Lixian LiuYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Hua RongYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Zhiqiang XuFaculty of Food Science, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Ying HuangYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Dahai GuYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Xiaobo ChenYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Wenyuan HuYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Jiarong ZhangYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Sumei ZhaoYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Markandeya JoisDepartment of Agricultural Sciences, School of Life Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora, VIC, 3086, Australia.
Qihua LiYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Changrong GeYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Marinus F W Te PasAnimal Breeding and Genomics Centre, Wageningen UR Livestock Research, Wageningen University and Research Centre, Building 107, Radix, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands. marinus.tepas@wur.nl.
Junjing JiaYunnan Provincial Key Laboratory of Animal Nutrition and Feed, Yunnan Agricultural University, Kunming, 650201, Yunnan Province, People's Republic of China.
Yunnan Agricultural University · CNLa Trobe University · AUWageningen University & Research · NL

Funding

National Natural Science Foundation of China 31560618National Natural Science Foundation of China 31572359National Natural Science Foundation of China U1702232National Science and Technology Program in the 13th Five-Year Plan 2015BAD03B03-4Natural Science Foundation of Yunnan Province (CN) 2016FA046Natural Science Foundation of Yunnan Province (CN) 2017IC048
6 · The paper itself

Abstract

Myostatin is a negative regulator of skeletal muscle growth. Muscle tissue is the largest tissue in the body and influences body growth. Commercial Avian broiler chickens are selected for high growth rate and muscularity. Daweishan mini chickens are a slow growing small-sized chicken breed. We investigated the relations between muscle (breast and leg) myostatin mRNA expression and body and muscle growth. Twenty chickens per breed were slaughtered at 0, 30, 60, 90, 120, and 150 days of age. Body and muscle weights were higher at all times in Avian chickens. Breast muscle myostatin expression was higher in Avian chickens than in Daweishan mini chickens at day 30. Myostatin expression peaked at day 60 in Daweishan mini chickens and expression remained higher in breast muscle. Daweishan mini chickens myostatin expression correlated positively with carcass weight, breast and leg muscle weight from day 0 to 60, and correlated negatively with body weight from day 90 to 150, while myostatin expression in Avian chickens was negatively correlated with carcass and muscle weight from day 90 to 150. The results suggest that myostatin expression is related to regulation of body growth and muscle development, with two different regulatory mechanisms that switch between days 30 and 60.

Indexed as

Animal HusbandryAnimalsAvian ProteinsBreedingChickensGene ExpressionGene Expression RegulationMuscle DevelopmentMuscle, SkeletalMyostatinPhenotypeRNA, MessengerAvian ProteinsMyostatinRNA, MessengerCommercial broiler chickenDaweishan mini chickenGrowth ratemRNA expressionMuscle weightMyostatin

Identifiers

PMID29740785
PMCPMC6060753
OpenAlexW2802178258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.