Evidence map›Paper›PMID 29740671›Full record

ArticleAnalytical and bioanalytical chemistry2018

Synchrotron- and focal plane array-based Fourier-transform infrared spectroscopy differentiates the basalis and functionalis epithelial endometrial regions and identifies putative stem cell regions of human endometrial glands.

Georgios Theophilou, Camilo L M Morais, Diane E Halliwell, Kássio M G Lima, Josephine Drury, Pierre L Martin-Hirsch, Helen F Stringfellow, Dharani K Hapangama, Francis L Martin

Open access · hybridAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Synchrotron Infrared Microspectroscopy for Stem Cell Research.International journal of molecular sciences · 2022
    Review
  6. Review
  7. Review
  8. Article
  9. Interrogation ofCancers · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Georgios TheophilouDepartment of Gynaecology, Leeds Teaching Hospitals NHS Foundation Trust, Leeds, LS1 3EX, UK.
Camilo L M MoraisSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE, UK.
Diane E HalliwellSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE, UK.
Kássio M G LimaBiological Chemistry and Chemometrics, Institute of Chemistry, Federal University of Rio Grande do Norte, Natal, 59072-970, Brazil.
Josephine DruryDepartment of Obstetrics and Gynaecology, Liverpool Women's NHS Foundation Trust, Liverpool, L8 7SS, UK.
Pierre L Martin-HirschDepartment of Obstetrics and Gynaecology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Fulwood, Preston, PR2 9HT, UK.
Helen F StringfellowDepartment of Obstetrics and Gynaecology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Fulwood, Preston, PR2 9HT, UK.
Dharani K HapangamaDepartment of Obstetrics and Gynaecology, Liverpool Women's NHS Foundation Trust, Liverpool, L8 7SS, UK.
Francis L MartinSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE, UK. flmartin@uclan.ac.uk.
University of Central Lancashire · GBUniversity of Liverpool · GBLancashire Teaching Hospitals NHS Foundation Trust · GBLeeds Teaching Hospitals NHS Trust · GBRoyal Preston Hospital · GBUniversidade Federal do Rio Grande do Norte · BR

Funding

CAPES-Brazil 88881.128982/2016-01Conselho Nacional de Desenvolvimento Científico e Tecnológico 305962/2014-0
6 · The paper itself

Abstract

The cyclical process of regeneration of the endometrium suggests that it may contain a cell population that can provide daughter cells with high proliferative potential. These cell lineages are clinically significant as they may represent clonogenic cells that may also be involved in tumourigenesis as well as endometriotic lesion development. To determine whether the putative stem cell location within human uterine tissue can be derived using vibrational spectroscopy techniques, normal endometrial tissue was interrogated by two spectroscopic techniques. Paraffin-embedded uterine tissues containing endometrial glands were sectioned to 10-μm-thick parallel tissue sections and were floated onto BaF

Indexed as

AdultEndometriumEpithelial CellsEquipment DesignFemaleHumansMultivariate AnalysisSpectroscopy, Fourier Transform InfraredStem CellsSynchrotronsBiospectroscopyCell lineageChemometricsEndometriumFTIR spectroscopyStem cells

Identifiers

PMID29740671
PMCPMC6021468
OpenAlexW2802790665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.