ArticleContemporary clinical trials communications2017
A cross-cutting approach to enhancing clinical trial site success: The Department of Veterans Affairs' Network of Dedicated Enrollment Sites (NODES) model.
Article in Contemporary clinical trials communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global initiatives to improve clinical investigation efficiency: a scoping review of implemented system-level reforms.Frontiers in medicine · 2026Pooled it
- Utilization of stakeholder engagement to inform the identification of leading indicators for clinical research enrollment performance in a large integrated health care system: The VA clinical research enrollment summit.Contemporary clinical trials communications · 2026Article
- Addressing challenges and barriers to rural Veteran participation in clinical research within the Veterans Affairs healthcare system.Contemporary clinical trials communications · 2025Article
- Utilization of a structured research site mentorship model to facilitate site performance in a clinical research network.Contemporary clinical trials communications · 2025Article
- INviting Veterans InTo Enrollment in Alzheimer's Disease Research Centers (INVITE-ADRC): An NIA and VA-sponsored initiative to increase veteran participation in aging and dementia research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- The VA Research Enterprise: A Platform for National Partnerships Toward Evidence Building and Scientific Innovation.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023Article
- VA Lessons From Partnering in COVID-19 Clinical Trials.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023Article
- Clinical trial facilitators: A novel approach to support the execution of clinical research at the study site level.Contemporary clinical trials communications · 2023Article
- A Qualitative Scoping Review of Early-Terminated Clinical Trials Sponsored by the Department of Veterans Affairs Cooperative Studies Program From 2010 to 2020.Epidemiologic reviews · 2022Article
- COVID-19 site readiness initiative: Building clinical trial capacity for vaccine efficacy trials in Latin America in response to the pandemic.Vaccine: X · 2022Article
- Clinical trials proposed for the VA Cooperative Studies Program: Success rates and factors impacting approval.Contemporary clinical trials communications · 2021Article
- Increasing access to clinical research using an innovative mobile recruitment approach: The (MoRe) concept.Contemporary clinical trials communications · 2020Article
- Leveraging Veterans Health Administration Clinical and Research Resources to Accelerate Discovery and Testing in Precision Oncology.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2020Article
- An initiative using informatics to facilitate clinical research planning and recruitment in the VA health care system.Contemporary clinical trials communications · 2018Article
- Research site mentoring: A novel approach to improving study recruitment.Contemporary clinical trials communications · 2018Article
- Total integrated performance excellence system (TIPES): A true north direction for a clinical trial support center.Contemporary clinical trials communications · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecruitment into clinical trials remains a key determinant to study completion and success. While various strategies have been proposed, it is unclear how they apply across different populations, diseases, and/or study goals. The ability to effectively overcome challenges may require different approaches that more broadly focus on addressing obstacles among sites that cannot be overcome by individual studies.
methodsThe Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) established the Network of Dedicated Enrollment Sites (NODES) as a consortium of sites to generate systematic site-level solutions to more efficiently recruit in CSP studies. Initial activities identified priorities and developed approaches through team-based efforts. Metrics were also developed to assess overall network performance.
resultsNetwork efforts produced several new strategies and best practices for common problems in CSP research. Recruitment strategies included bringing studies to patients and developing data programs using algorithms for finding eligible patients. Efficiency efforts focused on cross-training and standardizing performance reports.
conclusionNODES addressed site challenges in clinical trial recruitment and management by taking an overall approach that looked at the system rather than individual studies. Practices and operational changes were implemented for CSP research related to recruitment, staff training and research methodology. The network activities suggest that team-based development of tools and insights may help better identify targets and increase efficiencies for clinical trials recruitment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.