Evidence map›Paper›PMID 29740596›Full record

ArticleeNeuro

Neuregulin 1 Type I Overexpression Is Associated with Reduced NMDA Receptor-Mediated Synaptic Signaling in Hippocampal Interneurons Expressing PV or CCK.

Dimitrios Kotzadimitriou, Wiebke Nissen, Melinda Paizs, Kathryn Newton, Paul J Harrison, Ole Paulsen, Karri Lamsa

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Structural Organization of Perisomatic Inhibition in the Mouse Medial Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dimitrios KotzadimitriouDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.ORCID 0000-0001-5894-6569
Wiebke NissenDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.
Melinda PaizsDepartment of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, 6720, Hungary.
Kathryn NewtonDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.
Paul J HarrisonDepartment of Psychiatry, University of Oxford, and Oxford Health NHS Foundation Trust, Oxford, UK.ORCID 0000-0002-6719-1126
Ole PaulsenDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2258-5455
Karri LamsaDepartment of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.ORCID 0000-0002-4609-1337
University of Oxford · GBUniversity of Szeged · HUOxford Health NHS Foundation Trust · GBUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research CouncilMedical Research CouncilWellcome Trust
6 · The paper itself

Abstract

Hypofunction of

Indexed as

Signal TransductionAnimalsHippocampusInterneuronsMice, TransgenicNeuregulin-1ParvalbuminsReceptor, ErbB-4Receptors, N-Methyl-D-AspartateSchizophreniaErbb4 protein, mouseNeuregulin-1Nrg1 protein, mouseParvalbuminsReceptor, ErbB-4Receptors, N-Methyl-D-AspartateAxo-axonic cellbasket cellcholecystokininErbB4 receptorNMDA receptorsparvalbuminschizophrenia

Identifiers

PMID29740596
PMCPMC5938717
OpenAlexW2799325382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.