ReviewJournal of exercise rehabilitation2018
Low back pain, obesity, and inflammatory markers: exercise as potential treatment.
Review in Journal of exercise rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- The Influence of Exercise Intensity on Psychosocial Outcomes in Musculoskeletal Disorders: A Systematic Review.Sports healthPooled it
- Effects of Virtual Reality Exercises versus Isokinetic Exercises in comparison with Conventional Exercises on the Imaging Findings and Inflammatory Biomarker Changes in Soccer Players with Non-Specific Low Back Pain: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- The association of biomarkers with pain and function in acute and subacute low back pain: a secondary analysis of an RCT.BMC musculoskeletal disorders · 2022Trial
- High Intensity Training Is an Effective Modality to Improve Long-Term Disability and Exercise Capacity in Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Isokinetic training - its radiographic and inflammatory effects on chronic low back pain: A randomized controlled trial.Medicine · 2020Trial
- Hot Water Extract ofNutrients · 2019Trial
- Visceral Obesity and Its Complications: The Role of Bioelectrical Impedance Analysis in Longevity Medicine.Metabolites · 2026Review
- Global Burden and Forecasting of Musculoskeletal Disability Attributable to High BMI, 1990-2040: A GBD 2021 and Mendelian Randomization Study.Journal of pain research · 2026Article
- What a pain in the back: etiology, diagnosis and future treatment directions for discogenic low back pain.Bone research · 2025Review
- Causal relationship between trunk and lower limb fat mass and intervertebral disc disorders: A 2-sample Mendelian randomization study.Medicine · 2025Article
- Serum Interleukin-8 Levels and Their Association with Anxiety and Functional Disability in Military Personnel with Chronic Low Back Pain.Journal of clinical medicine · 2025Article
- Bridging the gap: Integrating exercise mimicry into chronic disease management through suppressing chronic inflammation.Journal of advanced research · 2025Review
- Article
- Global, regional, and national burden of low back pain for adults aged 55 and older 1990-2021: an analysis for the global burden of disease study 2021.BMC musculoskeletal disorders · 2025Article
- Impact of Socioeconomic Status on the Risk of Intervertebral Disc Degeneration and Low Back Pain in the European Population and the Mediating Role of Obesity-Related Traits: Evidence from a Mendelian Randomization Study.Journal of pain research · 2025Article
- The relationship of serum adiponectin and leptin levels with pain, function and intervertebral disc degeneration in patients with chronic low back pain.Turkish journal of physical medicine and rehabilitation · 2024Article
- Factors associated with pain-related functional interference in people with chronic low back pain enrolled in a physical exercise programme: the role of pain, sleep, and quality of life.Journal of rehabilitation medicine · 2024Article
- Spinal pain prevalence and associated determinants: A population-based study using the National Survey for Wales.Physiological reports · 2024Article
- Immune response and cytokine profiles in post-laminectomy pain syndrome: comparative analysis after treatment with intrathecal opioids, oral opioids, and non-opioid therapies.Inflammopharmacology · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro- and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.