Evidence map›Paper›PMID 29740445›Full record

ArticleFrontiers in immunology2018

Loss of

Yan Zhou, Xiao Leng, Yan He, Yan Li, Yuan Liu, Yang Liu, Qiang Zou, Guixiu Shi, Yantang Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yan ZhouDepartment of Emergency, West China Second University Hospital and Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects, Ministry of Education, Sichuan University, Chengdu, China.
Xiao LengDepartment of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Yan HeDepartment of Rheumatology and Clinical Immunology, The First Affiliated Hospital, Xiamen University, Xiamen, China.
Yan LiDepartment of Rheumatology and Clinical Immunology, The First Affiliated Hospital, Xiamen University, Xiamen, China.
Yuan LiuDepartment of Rheumatology and Clinical Immunology, The First Affiliated Hospital, Xiamen University, Xiamen, China.
Yang LiuDepartment of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Qiang ZouDepartment of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Guixiu ShiDepartment of Rheumatology and Clinical Immunology, The First Affiliated Hospital, Xiamen University, Xiamen, China.
Yantang WangDepartment of Immunology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
Chengdu Medical College · CNFirst Affiliated Hospital of Xiamen University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T helper 17 (Th17) cells are crucial for the pathogenesis of multiple sclerosis (MS) in humans and experimental autoimmune encephalomyelitis (EAE) in animals. High frequency of Th17 cells and low sensitivity to activation-induced cell death (AICD) are detected in MS patients. However, the mechanisms underlying apoptosis resistance of T cells remain unclear.

Indexed as

ApoptosisAnimalsCaspasesCell DifferentiationDisease ProgressionEncephalomyelitis, Autoimmune, ExperimentalFemaleGene DeletionLymphocyte ActivationLymphocyte Specific Protein Tyrosine Kinase p56(lck)MaleMembrane ProteinsMiceSpinal CordTh17 CellsTh1 CellsCaspasesLymphocyte Specific Protein Tyrosine Kinase p56(lck)Membrane ProteinsPerp protein, mouseactivation-induced cell deathcaspase activationexperimental autoimmune encephalomyelitis/multiple sclerosisPerpT helper 17 cell

Identifiers

PMID29740445
PMCPMC5925960
OpenAlexW2797430213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.