Evidence map›Paper›PMID 29740427›Full record

ArticleFrontiers in immunology2018

Intestinal Microbiota at Engraftment Influence Acute Graft-Versus-Host Disease

Lijie Han, Hua Jin, Lizhi Zhou, Xin Zhang, Zhiping Fan, Min Dai, Qianyun Lin, Fen Huang, Li Xuan, Haiyan Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 89 citations in OpenAlex.

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  9. Differential regulatory effects ofFood chemistry. Molecular sciences · 2025
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  16. Graft-Versus-Host Disease Mouse Models: A Clinical-Translational Perspective.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lijie HanDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Hua JinDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Lizhi ZhouDepartment of Biostatistics, Southern Medical University, Guangzhou, China.
Xin ZhangDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhiping FanDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Min DaiDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qianyun LinDepartment of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fen HuangDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Li XuanDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Haiyan ZhangDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qifa LiuDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Southern Medical University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal models have indicated that intestinal microbiota influence acute graft-versus-host disease (aGVHD) by modulating immune homeostasis. But, in humans, the mechanism by which the microbiota induces aGVHD remains unclear. In this study, we investigated the relationship between the intestinal microbiota and T cell subsets in patients who undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT) to explore the mechanism by which microbiota induced aGVHD. Based on aGVHD, this study was categorized into two groups: grades II-IV aGVHD (aGVHD group,

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultBacteriaDNA, BacterialFemaleGastrointestinal MicrobiomeGraft vs Host DiseaseHumansMaleMiddle AgedRNA, Ribosomal, 16STh17 CellsT-Lymphocytes, RegulatoryYoung AdultDNA, BacterialRNA, Ribosomal, 16Sacute graft-versus-host diseaseallogeneic hematopoietic stem cell transplantationhistone acetylationimmune homeostasisintestinal microbiota

Identifiers

PMID29740427
PMCPMC5928130
OpenAlexW2800277078

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.