Evidence map›Paper›PMID 29740319›Full record

ArticleFrontiers in pharmacology2018

Pharmacological Blockade of Adenosine A

Yan Li, Xinran Pan, Yan He, Yang Ruan, Linshan Huang, Yuling Zhou, Zhidong Hou, Chaoxiang He, Zhe Wang, Xiong Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Adenosine AFrontiers in pharmacology · 2024
    Article
  2. Neuronal and astrocytic CB1R signaling differentially modulates goal-directed behavior and working memory by distinct temporal mechanisms.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  3. Striatopallidal adenosine ANeuropharmacology · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Indirect Medium Spiny Neurons in the Dorsomedial Striatum Regulate Ethanol-Containing Conditioned Reward Seeking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Yan LiDepartment of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Xinran PanSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Yan HeSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Yang RuanSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Linshan HuangSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Yuling ZhouSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Zhidong HouSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Chaoxiang HeSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Zhe WangDepartment of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Xiong ZhangDepartment of Neurology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Jiang-Fan ChenSchool of Optometry and Ophthalmology and Eye Hospital, The Institute of Molecular Medicine, Wenzhou Medical University, Wenzhou, China.
Affiliated Eye Hospital of Wenzhou Medical College · CNWenzhou Medical University · CNSecond Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The balance and smooth shift between flexible, goal-directed behaviors and repetitive, habitual actions are critical to optimal performance of behavioral tasks. The striatum plays an essential role in control of goal-directed versus habitual behaviors through a rich interplay of the numerous neurotransmitters and neuromodulators to modify the input, processing and output functions of the striatum. The adenosine receptors (namely A

Indexed as

adenosine A1 receptoradenosine A2A receptorgoal-directed behaviorhabitinstrumental behavior

Identifiers

PMID29740319
PMCPMC5928261
OpenAlexW2798185477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.