Evidence map›Paper›PMID 29740313›Full record

ArticleFrontiers in pharmacology2018

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study.

Michael M Mendelson, Roby Johannes, Chunyu Liu, Tianxiao Huan, Chen Yao, Xiao Miao, Joanne M Murabito, Josée Dupuis, Daniel Levy, Emelia J Benjamin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study in Caucasians.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Michael M MendelsonNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Roby JohannesHebrew SeniorLife, Harvard Medical School, Boston, MA, United States.
Chunyu LiuNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Tianxiao HuanNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Chen YaoNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Xiao MiaoInnovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Joanne M MurabitoNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Josée DupuisNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Daniel LevyNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Emelia J BenjaminNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Honghuang LinNational Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
Framingham Heart Study · USNaval Research Laboratory Information Technology DivisionBoston Children's Hospital · USHebrew SeniorLife · USNational Heart Lung and Blood Institute · USShanghai University of Traditional Chinese Medicine · CN

Funding

Framingham Project/LevyZIAHL006001 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVY, DANIEL · 2009 to 2025
$51.1M
Circulating Epigenetic Biomarkers for Personalized Cardiovascular Disease PreventionK99HL136875 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI MENDELSON, MICHAEL MAXWELL · 2017 to 2018
$330k
NHLBI NIH HHS K99 HL136875
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

association studiesDNA methylationepigenomeinflammationTNFR2 levels

Identifiers

PMID29740313
PMCPMC5928448
OpenAlexW2799758200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.