ReviewWorld journal of gastroenterology2018
Endoscopic management of Crohn's strictures.
Review in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Nutritional interventions in adult fibrostenotic Crohn's disease: A systematic review.Frontiers in nutrition · 2023Pooled it
- Systematic review: medical therapy for fibrostenosing Crohn's disease.Alimentary pharmacology & therapeutics · 2020Pooled it
- Beyond the Intestinal Mucosa in Long-Standing Inflammatory Bowel Disease: Consequences of Chronic Inflammation and Endoscopic Approaches to Diagnosis and Management.Medicina (Kaunas, Lithuania) · 2026Review
- Recent Endoscopic Technological Advancements in Crohn's Stricture Dilation.Current gastroenterology reports · 2026Review
- Surgery-induced and Associated Long-term Strictures.Clinics in colon and rectal surgery · 2026Review
- Discordance between MR enterography and endoscopic detection of Crohn's disease ileal strictures: evidence to inform recommendations.Abdominal radiology (New York) · 2025Article
- Infective Endocarditis After Endoscopic Stricture Dilation in Crohn's Disease.ACG case reports journal · 2024Article
- Initial safety and efficacy of a novel drug-coated balloon for treatment of benign intestinal strictures.iGIE : innovation, investigation and insights · 2024Article
- Endoscopic balloon dilation management for benign duodenal stenosis.Surgical endoscopy · 2023Article
- Treatment escalation and de-escalation decisions in Crohn's disease: Delphi consensus recommendations from Japan, 2021.Journal of gastroenterology · 2023Review
- Endoscopic Management of Luminal Strictures: Beyond Dilation.Digestive diseases and sciences · 2022Review
- A pilot study investigating the safety and feasibility of endoscopic dilation using a radial incision and cutting technique for benign strictures of the small intestine: a study protocol.Pilot and feasibility studies · 2022Article
- Therapeutic Endoscopy in Postoperative Pouch Complications.Clinics in colon and rectal surgery · 2022Review
- Metformin Ameliorates Chronic Colitis-Related Intestinal FibrosisFrontiers in pharmacology · 2022Article
- Worse outcomes and higher costs of care in fibrostenotic Crohn's disease: a real-world propensity-matched analysis in the USA.BMJ open gastroenterology · 2021Article
- Crohn's Disease Obstructions.Clinics in colon and rectal surgery · 2021Review
- The value of magnetic resonance enterography in diagnostic difficulties associated with Crohn's disease.Polish journal of radiology · 2021Article
- Crohn's strictures open with anti-mycobacterial antibiotic therapy: A retrospective review.World journal of gastrointestinal endoscopy · 2020Article
- IT Knife-Assisted Balloon Stricturoplasty in a Patient With Crohn's Disease.ACG case reports journal · 2020Article
- Strictures in Crohn's Disease: From Pathophysiology to Treatment.Digestive diseases and sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Symptomatic intestinal strictures develop in more than one third of patients with Crohn's disease (CD) within 10 years of disease onset. Strictures can be inflammatory, fibrotic or mixed and result in a significant decline in quality of life, frequently requiring surgery for palliation of symptoms. Patients under the age of 40 with perianal disease are more likely to suffer from disabling ileocolonic disease thus may have a greater risk for fibrostenotic strictures. Treatment options for fibrostenotic strictures are limited to endoscopic and surgical therapy. Endoscopic balloon dilatation (EBD) appears to be a safe, less invasive and effective alternative modality to replace or defer surgery. Serious complications are rare and occur in less than 3% of procedures. For non-complex strictures without adjacent fistulizaation or perforation that are less than 5 cm in length, EBD should be considered as first-line therapy. The aim of this review is to present the current literature on the endoscopic management of small bowel and colonic strictures in CD, which includes balloon dilatation, adjuvant techniques of intralesional injection of steroids and anti-tumor necrosis factor, and metal stent insertion. Short and long-term outcomes, complications and safety of EBD will be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.