Evidence map›Paper›PMID 29740195›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Prenatal counseling and parental decision-making following a fetal diagnosis of trisomy 13 or 18.

Phoebe Winn, Krishna Acharya, Erika Peterson, Steven Leuthner

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Outcomes of patients with trisomy 13 and 18 in a center with a dedicated perinatal palliative care program.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Phoebe WinnDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Krishna AcharyaDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Erika PetersonDepartment of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.
Steven LeuthnerDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA. sleuthne@mcw.edu.
Medical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate parental decisions following a prenatal diagnosis of trisomy 13 (T13) or trisomy 18 (T18), prenatal counseling received, and pregnancy outcomes. STUDY

designSingle-center, retrospective cohort study of families with a prenatal diagnosis of T13 or T18 from 2000 to 2016.

resultsOut of 152 pregnancies, 55% were terminated. Twenty percent chose induction with palliative care, 20% chose expectant management, 2% chose full interventions, and 3% were lost to follow-up. Counseling was based on initial parental goals, but most women were given options besides termination. Women who chose expectant management had a live birth in 50% of the cases. Women who chose neonatal interventions had a live birth in 100% of the cases, but there were no long-term survivors.

conclusionsThe majority of women who continue their pregnancy after a fetal diagnosis of T13 or T18 desire expectant management with palliative care. A live birth can be expected at least half of the time.

Indexed as

Decision MakingPregnancy OutcomeCohort StudiesDirective CounselingFemaleHumansInfant, NewbornLive BirthMaleParentsPregnancyPrenatal CarePrenatal DiagnosisPrognosisRetrospective StudiesSurvival Analysis

Identifiers

PMID29740195
OpenAlexW2802161934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.