ArticleScientific reports2018
Distributed representation of pelvic floor muscles in human motor cortex.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05557175 (A Mixed-methods Evaluation of the Clinical and Cost-effectiveness of Repetitive Transcranial Magnetic Stimulation), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Mixed-methods Evaluation of the Clinical and Cost-effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Neurogenic Overactive Bladder in Stroke
Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Acute Effect of Transcranial Direct Current Stimulation in Pelvic Floor Muscle Function in Young Healthy Women: Initial Findings of a Randomized Controlled Trial.International urogynecology journal · 2024Trial
- Neuromotor modules revealed by direct electrical stimulation of the human primary motor cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Exploring brain activity differences in functional constipation using fNIRS: a case-control study.Journal of neuroengineering and rehabilitation · 2026Article
- Functional and Structural Characteristics of the Pelvic Floor in Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS).Journal of pain research · 2025Article
- Article
- Coactivation of the Pelvic Floor and Gluteus Medius Muscles While Walking and Running in Female Runners.Sensors (Basel, Switzerland) · 2024Article
- Reliability of a method to assess corticomotor excitability of lower limb muscles using a normalized EMG motor thresholding procedure.Scientific reports · 2024Article
- Implicit Motor Imagery for Chronic Pelvic Pain: A Cross-Sectional Case-Control Study.Journal of clinical medicine · 2023Article
- Article
- Impaired Ability to Relax Pelvic Floor Muscles in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome.Physical therapy · 2022Article
- When Two Is Better Than One: A Pilot Study on Transcranial Magnetic Stimulation Plus Muscle Vibration in Treating Chronic Pelvic Pain in Women.Brain sciences · 2022Article
- Effects of motor stimulation of the tibial nerve on corticospinal excitability of abductor hallucis and pelvic floor muscles.Frontiers in rehabilitation sciences · 2022Article
- Characterizing Pelvic Floor Muscle Activity During Walking and Jogging in Continent Adults: A Cross-Sectional Study.Frontiers in human neuroscience · 2022Article
- Corticomotor excitability of gluteus maximus and hip extensor strength: The influence of sex.Human movement science · 2021Article
- Natural bladder filling alters resting brain function at multiple spatial scales: a proof-of-concept MAPP Network Neuroimaging Study.Scientific reports · 2020Article
- Salience network functional connectivity is spatially heterogeneous across sensorimotor cortex in healthy humans.NeuroImage · 2020Article
- Whole brain 7T-fMRI during pelvic floor muscle contraction in male subjects.Neurourology and urodynamics · 2020Article
- Motor cortical neuromodulation of pelvic floor muscle tone: Potential implications for the treatment of urologic conditions.Neurourology and urodynamics · 2019Article
- Is Pelvic Floor Dysfunction Associated With Development of Transient Low Back Pain During Prolonged Standing? A Protocol.Clinical medicine insights. Women's health · 2019Article
- Improvement of Urinary Incontinence, Life Impact, and Depression and Anxiety With Modified Pelvic Floor Muscle Training After Radical Prostatectomy.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Human motor cortex can activate pelvic floor muscles (PFM), but the motor cortical representation of the PFM is not well characterized. PFM representation is thought to be focused in the supplementary motor area (SMA). Here we examine the degree to which PFM representation is distributed between SMA and the primary motor cortex (M1), and how this representation is utilized to activate the PFM in different coordination patterns. We show that two types of coordination patterns involving PFM can be voluntarily accessed: one activates PFM independently of synergists and a second activates PFM prior to and in proportion with synergists (in this study, the gluteus maximus muscle - GMM). Functional magnetic resonance imaging (fMRI) showed that both coordination patterns involve overlapping activation in SMA and M1, suggesting the presence of intermingled but independent neural populations that access the different patterns. Transcranial magnetic stimulation (TMS) confirmed SMA and M1 representation for the PFM. TMS also showed that, equally for SMA and M1, PFM can be activated during rest but GMM can only be activated after voluntary drive to GMM, suggesting that these populations are distinguished by activation threshold. We conclude that PFM representation is broadly distributed in SMA and M1 in humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.