Evidence map›Paper›PMID 29740095›Full record

ArticleScientific reports2018

Biofabrication of in situ Self Assembled 3D Cell Cultures in a Weightlessness Environment Generated using Magnetic Levitation.

Muge Anil-Inevi, Sena Yaman, Ahu Arslan Yildiz, Gulistan Mese, Ozden Yalcin-Ozuysal, H Cumhur Tekin, Engin Ozcivici

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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  18. Bioprinting in Microgravity.ACS biomaterials science & engineering · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muge Anil-IneviDepartment of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey.
Sena YamanDepartment of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey.
Ahu Arslan YildizDepartment of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey.
Gulistan MeseDepartment of Molecular Biology and Genetics, Izmir Institute of Technology, Urla, Izmir, Turkey.
Ozden Yalcin-OzuysalDepartment of Molecular Biology and Genetics, Izmir Institute of Technology, Urla, Izmir, Turkey.
H Cumhur TekinDepartment of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey. cumhurtekin@iyte.edu.tr.
Engin OzciviciDepartment of Bioengineering, Izmir Institute of Technology, Urla, Izmir, Turkey. enginozcivici@iyte.edu.tr.ORCID 0000-0003-4464-0475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic levitation though negative magnetophoresis is a novel technology to simulate weightlessness and has recently found applications in material and biological sciences. Yet little is known about the ability of the magnetic levitation system to facilitate biofabrication of in situ three dimensional (3D) cellular structures. Here, we optimized a magnetic levitation though negative magnetophoresis protocol appropriate for long term levitated cell culture and developed an in situ 3D cellular assembly model with controlled cluster size and cellular pattern under simulated weightlessness. The developed strategy outlines a potential basis for the study of weightlessness on 3D living structures and with the opportunity for real-time imaging that is not possible with current ground-based simulated weightlessness techniques. The low-cost technique presented here may offer a wide range of biomedical applications in several research fields, including mechanobiology, drug discovery and developmental biology.

Identifiers

PMID29740095
PMCPMC5940762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.