Evidence map›Paper›PMID 29740042›Full record

ArticleScientific reports2018

Evidence of CD4

Michaela Lucas, Pooja Deshpande, Ian James, Andri Rauch, Katja Pfafferott, Elouise Gaylard, Shahzma Merani, Anne Plauzolles, Andrew Lucas, Wyatt McDonnell and 15 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. COVID-19 Pandemic: Escape of Pathogenic Variants and MHC Evolution.International journal of molecular sciences · 2022
    Article
  5. Review
  6. Review
  7. Article
  8. Adaptive Immune Response against Hepatitis C Virus.International journal of molecular sciences · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 7 countries.

Michaela LucasSchool of Medicine and Pharmacology, Harry Perkins Institute and School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia.
Pooja DeshpandeSchool of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Ian JamesInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Andri RauchDivision of Infectious Diseases, University Hospital Bern and University of Bern, Bern, Switzerland.
Katja PfafferottInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Elouise GaylardInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Shahzma MeraniSchool of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Anne PlauzollesSchool of Human Sciences, University of Western Australia, Crawley, Western Australia, Australia.
Andrew LucasInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Wyatt McDonnellDivision of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0003-3859-2067
Spyros KalamsDivision of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Mark PilkintonDivision of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Cody ChastainDivision of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Louise BarnettDivision of Infectious Disease, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Amy ProsserInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Simon MallalInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Karen FitzmauricePeter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Heidi DrummerDepartment of Immunology and Department of Microbiology, Monash University, Victoria, Australia.
M Azim AnsariPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.ORCID 0000-0003-2790-8353
Vincent PedergnanaWellcome Trust Centre for Human Genetics, Oxford, UK.
Ellie BarnesPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Mina JohnDepartment of Immunology, Sir Charles Gairdner Hospital and Pathwest, Crawley, Western Australia, Australia.
Dermot KelleherDepartment of Clinical Medicine, Trinity College Dublin, Dublin, Ireland.
Paul KlenermanPeter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.
Silvana GaudieriInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia. silvana.gaudieri@uwa.edu.au.
Murdoch University · AUVanderbilt University Medical Center · USUniversity of Oxford · GBThe University of Western Australia · AUCentre for Human Genetics · GBRoyal Perth Hospital · AUThe University of Melbourne · AUUniversity of Alberta · CAUniversity of Bern · CHUniversity of British Columbia · CA

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Medical Research Council MR/K010239/1Medical Research Council MR/K01532X/1NIAID NIH HHS P30 AI110527Wellcome Trust 109965/Z/15/Z
6 · The paper itself

Abstract

Hepatitis C virus (HCV)-specific T cell responses are critical for immune control of infection. Viral adaptation to these responses, via mutations within regions of the virus targeted by CD8

Indexed as

Genome, ViralAllelesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCohort StudiesEpitopes, T-LymphocyteGene Expression RegulationGenotypeHepacivirusHepatitis C, ChronicHLA-DQ beta-ChainsHLA-DRB1 ChainsHost-Pathogen InteractionsHumansMutationViral Nonstructural ProteinsEpitopes, T-LymphocyteHLA-DQB1 antigenHLA-DQ beta-ChainsHLA-DRB1 ChainsViral Nonstructural Proteins

Identifiers

PMID29740042
PMCPMC5940905
OpenAlexW2807314079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.