Evidence map›Paper›PMID 29739970›Full record

ArticleScientific reports2018

Identifying microRNA determinants of human myelopoiesis.

Megha Rajasekhar, Ulf Schmitz, Stephane Flamant, Justin J-L Wong, Charles G Bailey, William Ritchie, Jeff Holst, John E J Rasko

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Sex differences in disease: sex chromosome and immunity.Journal of translational medicine · 2024
    Review
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  7. A regulatory network of microRNAs confers lineage commitment during early developmental trajectories of B and T lymphocytes.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Review
  9. Review
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Megha RajasekharGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
Ulf SchmitzGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
Stephane FlamantGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
Justin J-L WongGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
Charles G BaileyGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
William RitchieGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia.
Jeff HolstSydney Medical School, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-0377-9318
John E J RaskoGene & Stem Cell Therapy Program, Centenary Institute, University of Sydney, Camperdown, 2050, Australia. j.rasko@centenary.org.au.
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelopoiesis involves differentiation of hematopoietic stem cells to cellular populations that are restricted in their self-renewal capacity, beginning with the common myeloid progenitor (CMP) and leading to mature cells including monocytes and granulocytes. This complex process is regulated by various extracellular and intracellular signals including microRNAs (miRNAs). We characterised the miRNA profile of human CD34

Indexed as

ADP-ribosyl Cyclase 1Antigens, CD34Cell DifferentiationFetal BloodFucosyltransferasesGene Expression RegulationGene Expression Regulation, DevelopmentalGranulocytesHematopoietic Stem CellsHumansKruppel-Like Factor 4Kruppel-Like Transcription FactorsMicroRNAsMonocytesMyeloid Cell Leukemia Sequence 1 ProteinMyelopoiesisADP-ribosyl Cyclase 1Antigens, CD34FucosyltransferasesFUT4 protein, humanKLF4 protein, humanKruppel-Like Factor 4Kruppel-Like Transcription FactorsMCL1 protein, humanMicroRNAsMIRN10 microRNA, humanMIRN125 microRNA, humanMyeloid Cell Leukemia Sequence 1 Protein

Identifiers

PMID29739970
PMCPMC5940821
OpenAlexW2803371443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.