ArticleStroke2018
Longitudinal Change of Perceived Salt Intake and Stroke Risk in a Chinese Population.
Article in Stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 103 citations in OpenAlex.
- Total cholesterol, arterial stiffness, and systolic blood pressure: a mediation analysis.Scientific reports · 2021Trial
- Association of Newly Found Asymptomatic Intracranial Artery Stenosis and Ideal Cardiovascular Health Metrics in Chinese Community Population.Scientific reports · 2020Trial
- Time-dependent association between progression of arterial stiffness and risk of incident chronic kidney disease: a cohort study in China.Diabetologia · 2026Article
- Attributable risk and time trend in hemorrhagic and ischemic stroke mortality due to high sodium intake in Zhenjiang City from 2010 to 2021: an Age-Period-Cohort (APC) analysis.Frontiers in stroke · 2026Article
- Neutrophil stalling does not mediate the increase in tau phosphorylation and the cognitive impairment associated with high salt diet.Cardiovascular research · 2025Article
- The association between sodium index and the risk of obesity in Korean and Chinese university students: a cross-sectional study.Korean journal of community nutrition · 2025Article
- Marital Failure and Subsequent Heart Failure: A Prospective Study.Journal of the American Heart Association · 2025Article
- Dietary salt, vascular dysfunction, and cognitive impairment.Cardiovascular research · 2025Review
- Predictive Capability of Dual Trajectories of Central Adiposity Indices Combined With Glucose for Cardiovascular Diseases.Journal of diabetes · 2025Article
- Temporal trends of ischemic stroke attributable to diet high in sodium in China from the global burden of disease study 2021.Frontiers in nutrition · 2025Article
- Association of LDL-C with stroke and all-cause mortality in hypertensive patients with high risk of ASCVD.Clinical hypertension · 2025Article
- Trends in cardiovascular and cerebrovascular health scores in the Kailuan population from 2006 to 2011.World journal of cardiology · 2024Article
- Associations between cardiac arrhythmias and cardiovascular disease incidence and all-cause mortality: the Kailuan study.BMC public health · 2024Article
- Pathways from insulin resistance to incident cardiovascular disease: a Bayesian network analysis.Cardiovascular diabetology · 2024Article
- Risk and effect modifiers for poor glycemic control among the chinese diabetic adults on statin therapy: the kailuan study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Relationship of sodium index with the obesity indicators of university students in Daegu, South Korea: a cross-sectional study.Korean journal of community nutrition · 2024Article
- Association between Urine Specific Gravity as a Measure of Hydration Status and Risk of Type 2 Diabetes: The Kailuan Prospective Cohort Study.Nutrients · 2024Article
- Healthy Sleep Pattern, Metabolic Diseases, and Risk of Stroke: The Kailuan Cohort Study.Nature and science of sleep · 2024Article
- Metabolic obesity phenotypes and the risk of cancer: a prospective study of the Kailuan cohort.Frontiers in endocrinology · 2024Article
- Examining the Association between Cigarette Smoking Quantity and Subjective Salt Taste Preference and Salt-Related Eating Behavior.Korean journal of family medicine · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
background and purposeData for a relationship between salt intake and stroke have been inconsistent. This inconstancy could be because of the majority of studies evaluated salt intake at a single time point, which may be insufficient to accurately characterize salt intake throughout the observation period.
methodsIncluded were 77 605 participants from the Kailuan study. We assessed perceived salt intake via questionnaire in 2006, 2008, and 2010. Salt intake trajectories from 2006 to 2010 were identified using latent mixture models. Incident stroke cases were identified from 2010 to 2015 and confirmed by review of medical records. Cox proportional hazards model was used to examine the association between salt intake trajectories and stroke risk after adjusting for possible confounders, including age, sex, lifestyle, social economic status, body mass index, use of medicines, blood pressure, and lipoprotein profiles.
resultsIdentified were 5 distinct salt intake trajectories: moderate-stable (n=59 241), moderate-decreasing (n=9268), moderate-increasing (n=2975), low-increasing (n=2879), and high-decreasing (n=3242). During the 5-year follow-up period, there were 1564 incident strokes cases. Compared with individuals with the moderate-stable salt intake trajectory, individuals with moderate-decreasing salt intake trajectory had significantly lower cerebral infarction stroke risk (adjusted hazard ratio, 0.76; 95% confidence interval, 0.63-0.92) but not intracerebral hemorrhage risk (adjusted hazard ratio, 0.84; 95% confidence interval, 0.55-1.29). Further adjustment for 2006 or 2010 perceived salt intakes generated similar results. When baseline perceived salt intake only was used as the exposure, a significant dose-response relationship between higher perceived salt intake and higher stroke risk was observed (
conclusionsChange in salt intake was associated with the stroke risk. These data support the dietary recommendation to the reduction of salt intake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.