Evidence map›Paper›PMID 29739900›Full record

ArticlemBio2018

Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection.

Nicanor Obaldia, Elamaran Meibalan, Juliana M Sa, Siyuan Ma, Martha A Clark, Pedro Mejia, Roberto R Moraes Barros, William Otero, Marcelo U Ferreira, James R Mitchell and 6 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 2 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 2 syntheses or guidelines pooled it, 195 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Tropism ofEmerging microbes & infections · 2026
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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Nicanor Obaldia *Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Elamaran Meibalan *Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-3832-8955
Juliana M SaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Siyuan MaDepartment of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.
Martha A ClarkDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Pedro MejiaDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Roberto R Moraes BarrosLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
William OteroTropical Medicine Research, Panama City, Panama.
Marcelo U FerreiraDepartment of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
James R MitchellDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Danny A MilnerDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Curtis HuttenhowerDepartment of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.
Dyann F WirthDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Manoj T DuraisinghDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.
Thomas E WellemsLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Matthias MartiDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA matthias.marti@glasgow.ac.uk.ORCID 0000-0003-1040-9566
Harvard University · USNational Institute of Allergy and Infectious Diseases · USInstituto Conmemorativo Gorgas de Estudios de la Salud · PABrigham and Women's Hospital · USUniversidade de São Paulo · BR

Funding

Malaria Drug Resistance and Disease VirulenceZIAAI000483 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI WELLEMS, THOMAS E · 2009 to 2025
$24.5M
Functional analysis of red blood cell determinants of Plasmodium invasionR01HL139337 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI DURAISINGH, MANOJ T · 2017 to 2020
$2.3M
Intramural NIH HHS ZIA AI000483NHLBI NIH HHS R01 HL139337Wellcome TrustWellcome Trust 104111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAotidaeBone MarrowFemaleHumansMalaria, FalciparumMalaria, VivaxMalePlasmodium falciparumPlasmodium vivaxProtozoan ProteinsSaimiriProtozoan ProteinsAotusblood-stage parasitesgametocytesimmunohistochemistrylaboratory animal modelsmalariareal-time PCRSaimiritranscriptome

Identifiers

PMID29739900
PMCPMC5941073
OpenAlexW2801703923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.