Evidence map›Paper›PMID 29739882›Full record

ArticleScience signaling2018

Gene expression kinetics governs stimulus-specific decoration of the

Xinyu Hong, H Deborah Chen, Eduardo A Groisman

Open access · bronzeAbstract read
In one paragraph

Article in Science signaling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Analysis of stress-induced small proteins inbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Coordination of Phosphate and Magnesium Metabolism in Bacteria.Advances in experimental medicine and biology · 2022
    Article
  9. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  10. LpxT-Dependent Phosphorylation of Lipid A inFrontiers in microbiology · 2021
    Article
  11. Review
  12. Article
  13. Overexpression ofMicroorganisms · 2020
    Article
  14. Clofazimine Reduces the Survival ofACS infectious diseases · 2020
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xinyu HongDepartment of Cell Biology, Yale School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.ORCID 0000-0002-2419-4554
H Deborah ChenDepartment of Microbial Pathogenesis, Yale School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.
Eduardo A GroismanDepartment of Microbial Pathogenesis, Yale School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. eduardo.groisman@yale.edu.ORCID 0000-0001-6860-7691
Yale University · US

Funding

Expanding the SensingAbilities of Virulence Regulatory SystemsR01AI120558 · NIAID · YALE UNIVERSITY · PI GROISMAN, EDUARDO · 2016 to 2019
$2.2M
NIAID NIH HHS R01 AI120558
6 · The paper itself

Abstract

Lipid A is the innermost component of the lipopolysaccharide (LPS) molecules that occupy the outer leaflet of the outer membrane in Gram-negative bacteria. Lipid A is recognized by the host immune system and targeted by cationic antimicrobial compounds. In

Indexed as

Gene Expression Regulation, BacterialAnti-Bacterial AgentsBacterial ProteinsCell MembraneDrug Resistance, BacterialKineticsLipid AMagnesiumPolymyxin BSalmonella typhimuriumAnti-Bacterial AgentsBacterial ProteinsLipid AMagnesiumPhoP protein, BacteriapmrA protein, BacteriaPolymyxin B

Identifiers

PMID29739882
PMCPMC5967240
OpenAlexW2801654081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.