Evidence map›Paper›PMID 29739871›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Canonical

Daniel B Herrick, Zhen Guo, Woochan Jang, Nikolai Schnittke, James E Schwob

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Olfactory models as a platform for neuroscience research.Frontiers in cellular neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel B HerrickProgram in Cell, Molecular, and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston Massachusetts 02111.ORCID 0000-0003-1066-4751
Zhen GuoProgram in Cell, Molecular, and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston Massachusetts 02111.
Woochan JangDepartment of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston Massachusetts 02111.ORCID 0000-0002-9935-8103
Nikolai SchnittkeProgram in Cell, Molecular, and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston Massachusetts 02111.
James E SchwobDepartment of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston Massachusetts 02111 jim.schwob@tufts.edu.ORCID 0000-0001-8902-5260
Tufts University · US

Funding

REGULATION OF NEUROGENESIS IN OLFACTORY EPITHELIUMR01DC002167 · NIDCD · UPSTATE MEDICAL UNIVERSITY · PI SCHWOB, JAMES E. · 1994 to 2016
$5.2M
The regulation of p63 expression and activation to multipotency in HBCs of the olF30DC013962 · NIDCD · TUFTS UNIVERSITY BOSTON · PI HERRICK, DANIEL · 2014 to 2018
$193k
Olfactory Epithelial Stem Cell Regulation by the Transcription Factor p63F30DC011241 · NIDCD · TUFTS UNIVERSITY BOSTON · PI SCHNITTKE, NIKOLAI · 2010 to 2013
$151k
NIDCD NIH HHS F30 DC011241NIDCD NIH HHS F30 DC013962NIDCD NIH HHS R01 DC002167
6 · The paper itself

Abstract

The adult olfactory epithelium (OE) has the remarkable capacity to regenerate fully both neurosensory and non-neuronal cell types after severe epithelial injury. Lifelong persistence of two stem cell populations supports OE regeneration when damaged: the horizontal basal cells (HBCs), dormant and held in reserve; and globose basal cells, a heterogeneous population most of which are actively dividing. Both populations regenerate all cell types of the OE after injury, but the mechanisms underlying neuronal versus non-neuronal lineage commitment after recruitment of the stem cell pools remains unknown. We used both retroviral transduction and mouse lines that permit conditional cell-specific genetic manipulation as well as the tracing of progeny to study the role of canonical

Indexed as

AnimalsCell DifferentiationImmunoglobulin J Recombination Signal Sequence-Binding ProteinMaleMiceMice, Inbred C57BLMice, KnockoutNeural Stem CellsNeurogenesisNuclear ProteinsOlfactory MucosaRatsRats, Sprague-DawleyReceptor, Notch1Receptor, Notch2Receptors, NotchImmunoglobulin J Recombination Signal Sequence-Binding ProteinMaml1 protein, mouseNotch1 protein, mouseNotch2 protein, mouseNuclear ProteinsRbpj protein, mouseReceptor, Notch1Receptor, Notch2Receptors, NotchTranscription Factorsadult neurogenesiscanonicalchemical sensesNotch1Notch signalingRBPJ

Identifiers

PMID29739871
PMCPMC5966796
OpenAlexW2801115439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.