Evidence map›Paper›PMID 29739854›Full record

ArticleThe Journal of biological chemistry2018

From micelles to bicelles: Effect of the membrane on particulate methane monooxygenase activity.

Soo Y Ro, Matthew O Ross, Yue Wen Deng, Sharon Batelu, Thomas J Lawton, Joseph D Hurley, Timothy L Stemmler, Brian M Hoffman, Amy C Rosenzweig

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Structures of methane and ammonia monooxygenases in native membranes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Methane Oxidation to Methanol.Chemical reviews · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Soo Y RoFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Matthew O RossFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Yue Wen DengFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Sharon Bateluthe Department of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48201.
Thomas J LawtonFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Joseph D HurleyFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Timothy L Stemmlerthe Department of Pharmaceutical Sciences, Wayne State University, Detroit, Michigan 48201.
Brian M HoffmanFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and.
Amy C RosenzweigFrom the Departments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 and amyr@northwestern.edu.ORCID 0000-0001-8472-4134
Northwestern University · USWayne State University · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Metalloenzymes and metal homeostasisR35GM118035 · NIGMS · NORTHWESTERN UNIVERSITY · PI AMY C. ROSENZWEIG · 2016 to 2026
$7.1M
Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
Molecular Biophysics Training Program at Northwestern UniversityT32GM008382 · NIGMS · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 1990 to 2020
$4.3M
Particulate Methane MonooxygenaseR01GM070473 · NIGMS · NORTHWESTERN UNIVERSITY · PI ROSENZWEIG, AMY C. · 2004 to 2015
$3.7M
Structural Insights into the Function of FrataxinR01DK068139 · NIDDK · WAYNE STATE UNIVERSITY · PI STEMMLER, TIMOTHY LOUIS · 2005 to 2015
$3.5M
NIDDK NIH HHS R01 DK068139NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM070473NIGMS NIH HHS R01 GM111097NIGMS NIH HHS R35 GM118035NIGMS NIH HHS T32 GM008382
6 · The paper itself

Abstract

Particulate methane monooxygenase (pMMO) is a copper-dependent integral membrane metalloenzyme that converts methane to methanol in methanotrophic bacteria. Studies of isolated pMMO have been hindered by loss of enzymatic activity upon its removal from the native membrane. To characterize pMMO in a membrane-like environment, we reconstituted pMMOs from

Indexed as

MicellesCell MembraneCopperCrystallography, X-RayMethaneMethylococcus capsulatusModels, MolecularOxidation-ReductionOxygenasesProtein ConformationCopperMethanemethane monooxygenaseMicellesOxygenasesbicellebiofuelbiotechnologycopper metalloenzymecopper monooxygenasecrystal structuremembrane proteinmetalloenzymemethane oxidationmethanotrophparticulate methane monooxygenaseprotein-lipid interaction

Identifiers

PMID29739854
PMCPMC6036204
OpenAlexW2799600259

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.