Evidence map›Paper›PMID 29739804›Full record

ArticleDisease models & mechanisms2018

Etiology and treatment of adrenoleukodystrophy: new insights from

Hannah B Gordon, Lourdes Valdez, Anthea Letsou

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulatory Changes in the Fatty Acid ElongasebioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Peroxisomal ABC Transporters: An Update.International journal of molecular sciences · 2021
    Review
  9. Evolution of adrenoleukodystrophy model systems.Journal of inherited metabolic disease · 2021
    Review
  10. Article
  11. X-linked adrenoleukodystrophy: Pathology, pathophysiology, diagnostic testing, newborn screening and therapies.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2020
    Review
  12. Review
  13. Rosy Beginnings: Studying Peroxisomes inFrontiers in cell and developmental biology · 2020
    Review
  14. What Peroxisomes (Don't) do to Mitochondria.Contact (Thousand Oaks (Ventura County, Calif.))
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hannah B GordonDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Lourdes ValdezDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Anthea LetsouDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA aletsou@genetics.utah.edu.ORCID 0000-0002-8538-7886
University of Utah · US

Funding

Modeling Neurodegeneration and Adrenoleukodystrophy in DrosophilaR01NS065474 · NINDS · UNIVERSITY OF UTAH · PI LETSOU, ANTHEA · 2009 to 2010
$737k
NINDS NIH HHS R01 NS065474
6 · The paper itself

Abstract

Adrenoleukodystrophy (ALD) is a fatal progressive neurodegenerative disorder affecting brain white matter. The most common form of ALD is X-linked (X-ALD) and results from mutation of the

Indexed as

AdrenoleukodystrophyAnimalsCentral Nervous SystemDrosophila melanogasterDrosophila ProteinsFatty AcidsGene-Environment InteractionMutationNerve DegenerationPenetranceRetinal NeuronsDrosophila ProteinsFatty AcidsABCD1Bubblegum (Bgm)Double bubble (Dbb)ElongaseFatty acid acyl-coA synthetaseFatty acid transporterNeurodegeneration

Identifiers

PMID29739804
PMCPMC6031365
OpenAlexW2799937650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.