ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2018
Prevalence of treatment-resistant hypertension after considering pseudo-resistance and morbidity: a cross-sectional study in Irish primary care.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of and associated factors for resistant hypertension in primary care settings: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- Current status of elevated blood pressure and hypertension among adolescents in Asia: a systematic review.Journal of global health · 2025Pooled it
- Supporting GPs and people with hypertension to maximise medication use to control blood pressure: a pilot cluster RCT of the MIAMI intervention.BMC primary care · 2024Trial
- Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real-World Single-Center Observational Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Observational
- Prevalence and determinants of apparent treatment-resistant hypertension among patients in South African primary care: a single-centre observational study.BMC cardiovascular disorders · 2025Observational
- Characterizing apparent treatment resistant hypertension in the United States: insights from the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Supporting General Practitioners and people with hypertension to maximise medication use to control blood pressure: the contribution of Collective Intelligence to the development of the 'Maximising Adherence, Minimising Inertia' (MIAMI) intervention.Health psychology and behavioral medicine · 2024Article
- Prevalence and determinants of resistant hypertension in the delta region of Egypt: A prospective observational study.Health science reports · 2023Article
- Supporting GPs and people with hypertension to maximise medication use to control blood pressure: Protocol for a pilot cluster RCT of the MIAMI intervention.HRB open research · 2023Article
- Introducing Advanced Paramedics into the rural general practice team in Ireland - general practitioners attitudes.BMC primary care · 2022Article
- Evidence of Nonadherence in Cases of Pseudoresistant Hypertension.Integrated blood pressure control · 2021Article
- Renal Denervation for Resistant Hypertension: Where Do We Stand?Current hypertension reports · 2020Review
- Blood pressure control in patients with a previous stroke/transient ischaemic attack in primary care in Ireland: a cross sectional study.BMC family practice · 2020Article
- Improvement of Blood Pressure Control by Adherence Check in Patients With Apparent Treatment-Resistant Hypertension: A Case Series.Clinical medicine insights. Case reports · 2020Article
- Measuring adherence to therapy in apparent treatment-resistant hypertension: a feasibility study in Irish primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Medication adherence and treatment-resistant hypertension: a review.Drugs in context · 2019Review
- Prognosis of patients with apparent treatment-resistant hypertension-a feasibility study.Pilot and feasibility studies · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo confirm treatment-resistant hypertension (TRH), ambulatory blood pressure measurement (ABPM) must exclude white-coat hypertension (WCH), three or more medications should be prescribed at the optimal doses tolerated, and non-adherence and lifestyle should be examined. Most previous studies have not adequately considered pseudo-resistance and merely provide an apparent TRH (aTRH) prevalence figure.
aimTo conduct a cross-sectional study of the prevalence of aTRH in general practice, and then consider pseudo-resistance and morbidity. DESIGN AND
settingWith support, 16 practices ran an anatomical therapeutic chemical (ATC) drug search, identifying patients on any possible hypertensive medications, and then a search of individual patients' electronic records took place.
methodABPM was used to rule out WCH. The World Health Organization-defined daily dosing guidelines determined adequate dosing. Adherence was defined as whether patients requested nine or more repeat monthly prescriptions within the past year.
resultsSixteen practices participated (
conclusionReviewing individual patient records results in a lower estimate of prevalence of TRH than has been previously reported. Further consideration for individual patients of pseudo-resistance additionally lowers these estimates, and may be all that is required for management in the vast majority of cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.