Evidence map›Paper›PMID 29739436›Full record

Trial reportRadiation oncology (London, England)2018

Re-irradiation in lung disease by SBRT: a retrospective, single institutional study.

Donatella Caivano, Maurizio Valeriani, Sara De Matteis, Paolo Bonome, Ivana Russo, Vitaliana De Sanctis, Giuseppe Minniti, Mattia Falchetto Osti

Abstract readClinical Trial
In one paragraph

Trial report in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Provider decision regret-a useful method for analysis of palliative thoracic re-irradiation for lung cancer?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donatella CaivanoDepartement of Radiation Oncology, CNAO (National Centre of Oncological Hadrontherapy), Str. Campeggi, 53, 27100, Pavia, Italy. donatella.caivano@gmail.com.
Maurizio ValerianiDepartment of Radiation Oncology, Faculty of "Medicina e Psicologia", University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035/1039, 00189, Rome, Italy.
Sara De MatteisDepartment of Radiation Oncology, Faculty of "Medicina e Psicologia", University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035/1039, 00189, Rome, Italy.
Paolo BonomeDepartment of Radiation Oncology, Faculty of "Medicina e Psicologia", University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035/1039, 00189, Rome, Italy.
Ivana RussoUPMC San Pietro FBF, Centro di Radioterapia ad alta specializzazione, Via Cassia 600, 00189, Roma, Italia.
Vitaliana De SanctisDepartment of Radiation Oncology, Faculty of "Medicina e Psicologia", University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035/1039, 00189, Rome, Italy.
Giuseppe MinnitiNeuromed - Mediterranean Neurological Institute, Via Atinense, 18, 86077, Pozzilli, (IS), Italy.
Mattia Falchetto OstiDepartment of Radiation Oncology, Faculty of "Medicina e Psicologia", University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035/1039, 00189, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe loco regional relapse is frequent in the lung disease. The aim of this study was to evaluate the outcomes of re-irradiation by SBRT in terms of Local Control (LC) and toxicities.

methodsFrom April 2011 to December 2016, twenty-two patients received a re-irradiation by SBRT. Twenty- seven lesions were treated. The medium BED(10) of re-irradiation was 100.6 Gy (range: 48-151.2 Gy) and the medium EQD2(10) was 93.8 Gy (range: 40-126 Gy). In the previous treatment the medium BED(10) was 97.2 Gy (range: 40-120 Gy), the medium EQD2(10) was 81 Gy (range: 32.5-100 Gy). The median time between the first and the second treatment was 18 months.

resultsLocal Control was reached in 18 out of 27 (66%) re-irradiated lesions, with rates of 67 and 54% at 1- year and 2- years respectively. The treatment was well tolerated; the maximum recorded toxicity was Grade 3.

conclusionsRe- irradiation by SBRT may represent an option for the treatment of lung disease with good results in terms of LC and toxicity.

Indexed as

AdenocarcinomaAgedAged, 80 and overCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedPrognosisRadiosurgeryRe-IrradiationRetrospective StudiesLungPrimary or metastatic diseaseRe-irradiationSBRT

Identifiers

PMID29739436
PMCPMC5941638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.