ArticleBMC cardiovascular disorders2018
The impact of nontraditional lipid profiles on left ventricular geometric abnormalities in general Chinese population.
Article in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 31 citations in OpenAlex.
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- The Relationship Between Ambulatory Blood Pressure and Atherogenic Index with LV Geometry Pattern in Obese Children: Results from a Cross-Sectional Study in Serbia.Pediatric cardiology · 2026Article
- The relationship between the ratio of triglyceride to high-density lipoprotein cholesterol and left ventricular hypertrophy in Chinese hypertension adults.Scientific reports · 2025Article
- Concentric remodeling and the metabolic-associated steatotic liver disease in patients with type 1 diabetes: an exploratory study.Acta diabetologica · 2025Article
- Longitudinal lipidomic profiles of left ventricular mass and left ventricular hypertrophy in American Indians.JCI insight · 2024Article
- Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study.Lipids in health and disease · 2024Article
- Higher LDL-C/HDL-C Ratio Is Associated with Elevated HbA1c and Decreased eGFR Levels and Cardiac Remodeling in Elderly with Hypercholesterolemia.Journal of cardiovascular development and disease · 2024Article
- Relationship between four insulin resistance surrogates and left ventricular hypertrophy among hypertensive adults: a case-control study.Endocrine connections · 2024Article
- Association between cardiometabolic index and congestive heart failure among US adults: a cross-sectional study.Frontiers in cardiovascular medicine · 2024Article
- Correlations of Serum Lipid Parameters and Atherogenic Indices With Left Ventricular Diastolic Dysfunction Among Apparently Healthy Patients With Type 2 Diabetes Mellitus: A Multicenter In-Hospital Cross-Sectional Study.Journal of diabetes research · 2024Article
- Value of the triglyceride-glucose index and non-traditional blood lipid parameters in predicting metabolic syndrome in women with polycystic ovary syndrome.Hormones (Athens, Greece) · 2023Article
- Combined superposition effect of hypertension and dyslipidemia on left ventricular hypertrophy.Animal models and experimental medicine · 2022Article
- Article
- The association of lipid ratios with hyperuricemia in a rural Chinese hypertensive population.Lipids in health and disease · 2021Article
- Association Between Lipid Accumulation Product and Target Organ Damage in Elderly Population: The Northern Shanghai Study.Clinical interventions in aging · 2021Article
- Clinical Profiles of Selected Biomarkers Identifying Infection and Cancer Patients: A Gorzów Hospital Example.Disease markers · 2019Article
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite current interest in the unfavorable impact of nontraditional lipid profiles on cardiovascular disease, information regarding its relations to abnormal left ventricular (LV) geometry has not been systemically elucidated. This study sought to understand predictive implication of nontraditional lipid profiles in specific LV geometric patterns in the general population of rural China.
methodsAnalyses were based upon a cross-sectional study of 10,756 participants (mean age 53.8 years; 54.0% females) who underwent assessment of biochemical, anthropometric, and blood pressure variables in rural areas of China. Participants were classified into four groups of LV morphologic pattern according to left ventricular mass index (LVMI) and relative wall thickness with quantitative echocardiographic data.
resultsBy multivariable-adjusted linear regression models, nontraditional lipid profiles were positive determinants of concentricity index and LV wall thickness (all P < 0.05), with modest effects on LVMI. Non-high-density lipoprotein cholesterol (non-HDL-C) emerged as an independent correlate of concentric LV hypertrophy (LVH) (adjusted odds ratio [OR]: 1.174 per 1 SD increment in non-HDL-C, 95% confidence interval [CI]: 1.075-1.281), followed by low-density lipoprotein cholesterol (LDL-C)/HDL-C ratio (1.158 [1.059-1.266]), total cholesterol (TC)/HDL-C ratio (1.150 [1.050-1.260]), and triglyceride (TG)/HDL-C ratio (1.134 [1.030-1.249]). The ORs for concentric LVH by tertiles further provided insight into that excess risk was associated with the highest tertile of nontraditional lipid profiles. The areas under the ROC curves to predict concentric LVH were statistically identical among nontraditional lipid parameters.
conclusionNontraditional lipid profiles, easily measured in the everyday routine examination, were responsible for increased risk of concentric LVH, potentially providing enhanced clinical utility at no additional cost, which emphasized the beneficial effect of these markers to supplement and improve CVD risk stratification.
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