Evidence map›Paper›PMID 29738243›Full record

ArticleJournal of natural products2018

Antiplasmodial Diterpenoids and a Benzotropolone from Petradoria pumila.

Yongle Du, Ana L Valenciano, Michael Goetz, Maria B Cassera, David G I Kingston

Abstract read
In one paragraph

Article in Journal of natural products, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yongle DuDepartment of Chemistry and the Virginia Tech Center for Drug Discovery, M/C 0212 , Virginia Tech , Blacksburg , Virginia 24061 , United States.
Ana L ValencianoDepartment of Biochemistry and Molecular Biology, and Center for Tropical and Emerging Global Diseases (CTEGD) , University of Georgia , Athens , Georgia 30602 , United States.ORCID 0000-0002-5516-7452
Michael GoetzNatural Products Discovery Institute , 3805 Old Easton Road , Doylestown , Pennsylvania 18902 , United States.
Maria B CasseraDepartment of Biochemistry and Molecular Biology, and Center for Tropical and Emerging Global Diseases (CTEGD) , University of Georgia , Athens , Georgia 30602 , United States.ORCID 0000-0001-6341-3169
David G I KingstonDepartment of Chemistry and the Virginia Tech Center for Drug Discovery, M/C 0212 , Virginia Tech , Blacksburg , Virginia 24061 , United States.ORCID 0000-0001-8944-246X

Funding

Discovery and Mechanism of Antimalarial Natural ProductsR01AT008088 · NCCIH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASSERA, MARIA BELEN, CLEMENT, JASON ANDERSON · 2014 to 2018
$2.0M
NCCIH NIH HHS R01 AT008088
6 · The paper itself

Abstract

An extract of Petradoria pumila from the Natural Products Discovery Institute was found to have moderate antiplasmodial activity, with an IC

Indexed as

AntimalarialsAsteraceaeBiflavonoidsCatechinDiterpenesLignansMagnetic Resonance SpectroscopyPlant ExtractsPlasmodium falciparumAntimalarialsbenzotropoloneBiflavonoidsCatechinDiterpenesLignansPlant Extracts

Identifiers

PMID29738243
PMCPMC7025711

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.