Evidence map›Paper›PMID 29737882›Full record

ArticleBiomarkers in medicine2018

A peripheral blood transcriptome biomarker test to diagnose functional recovery potential in advanced heart failure.

Mario C Deng

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Biomarkers in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05258942 (MyLeukoMAP™ Genomic Survival Prediction Assay for Heart Failure Pivotal Clinical Study), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05258942 unknown statusnot on this mapstarted 2022, after this paper: background citation

MyLeukoMAP™ Genomic Survival Prediction Assay for Heart Failure Pivotal Clinical Study

TypeobservationalSponsorLeukoLifeDx IncRan2022 to 2023Enrolled300ConditionsHeart FailureArmsObservational
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Multi-dimensional COVID-19 short- and long-term outcome prediction algorithm.Expert review of precision medicine and drug development · 2020
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Mario C DengProfessor of Medicine Advanced Heart Failure/Mechanical Support/Heart Transplant, David Geffen School of Medicine at UCLA, Ronald Reagan UCLA Medical Center, 100 Medical Plaza Drive, Suite 630, Los Angeles, CA 90095, USA.
GTx (United States) · US

Funding

Multidimensional Molecular Biomarkers of MultiOrgan Dysfunction after MCS TherapyR21HL120040 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DENG, MARIO C. · 2014 to 2015
$421k
NHLBI NIH HHS R21 HL120040
6 · The paper itself

Abstract

Heart failure (HF) is a complex clinical syndrome that causes systemic hypoperfusion and failure to meet the body's metabolic demands. In an attempt to compensate, chronic upregulation of the sympathetic nervous system and renin-angiotensin-aldosterone leads to further myocardial injury, HF progression and reduced O

Indexed as

Recovery of FunctionTranscriptomeAgedBiomarkersCoronary Artery BypassFemaleHeart FailureHumansMaleRiskBiomarkersadvanced heart failurebiomarkerfunctional recovery potentialheart transplantationmechanical circulatory supportrelational medicinerevascularizationshared decision-makingvalve replacementventricular tachycardia ablation

Identifiers

PMID29737882
PMCPMC6479277
OpenAlexW2802737935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.