Evidence map›Paper›PMID 29737465›Full record

ArticleJournal of molecular neuroscience : MN2018

GABA

Ravid Doron, Avital Sever, Assaf Handelsman, Roni Toledano, Motty Franko, Yafit Hirshler, Alon Shamir, Or Burstein, Moshe Rehavi

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ravid DoronSchool of Behavioral Sciences, The Academic College Tel Aviv Yaffo, 6818211, Tel Aviv, Israel. raviddor@mta.ac.il.ORCID http://orcid.org/0000-0002-6523-9886
Avital SeverDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, 6997801, Tel Aviv, Israel.
Assaf HandelsmanSchool of Behavioral Sciences, The Academic College Tel Aviv Yaffo, 6818211, Tel Aviv, Israel.
Roni ToledanoDepartment of Education and Psychology, The Open University of Israel, 4353701, Ra'anana, Israel.
Motty FrankoSchool of Behavioral Sciences, The Academic College Tel Aviv Yaffo, 6818211, Tel Aviv, Israel.
Yafit HirshlerDepartment of Education and Psychology, The Open University of Israel, 4353701, Ra'anana, Israel.
Alon ShamirFaculty of Medicine, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.
Or BursteinSchool of Behavioral Sciences, The Academic College Tel Aviv Yaffo, 6818211, Tel Aviv, Israel.
Moshe RehaviDepartment of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, 6997801, Tel Aviv, Israel.
Academic College of Tel Aviv-Yafo · ILOpen University of Israel · ILTel Aviv University · ILTechnion – Israel Institute of Technology · IL

Funding

Israel Science Foundation ISF 738/11Ministry of Science and Technology, Israel 3-13552National Institute for Psychobiology in Israel, Hebrew University of Jerusalem NIPI-7-2011-12
6 · The paper itself

Abstract

Anxiety disorders are highly prevalent and considered a major public health concern worldwide. Current anxiolytics are of limited efficacy and associated with various side effects. Our novel herbal treatment (NHT), composed of four constituents, was shown to reduce anxiety-like behavior while precluding a common side effect caused by current anxiolytics, i.e., sexual dysfunction. Nevertheless, NHT's mechanism of action is yet to be determined. There is evidence that some medicinal herbs interact with the GABAergic system. Therefore, we aimed to examine whether NHT's anxiolytic-like effect is exerted by alterations in GABA

Indexed as

AnimalsAnti-Anxiety AgentsAnxietyBrainClonazepamMaleMaze LearningMiceMice, Inbred C57BLPlant ExtractsReceptors, GABA-AAnti-Anxiety AgentsClonazepamPlant ExtractsReceptors, GABA-AAnxietyBenzodiazepinesGABAA receptorHerbal treatmentStress

Identifiers

PMID29737465
OpenAlexW2799541662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.