SynthesisCurrent environmental health reports2018
Breastfeeding as a Predictor of Serum Concentrations of Per- and Polyfluorinated Alkyl Substances in Reproductive-Aged Women and Young Children: A Rapid Systematic Review.
Synthesis in Current environmental health reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Perfluorooctanoic Acid (PFOA) Exposure in Early Life Increases Risk of Childhood Adiposity: A Meta-Analysis of Prospective Cohort Studies.International journal of environmental research and public health · 2018Pooled it
- Serum PFAS concentrations and neuromorphometry in adolescents: The HOME Study.Environmental research · 2026Article
- Associations between serum per- and polyfluoroalkyl substance concentrations and β-cell function and insulin resistance in adult females.The Journal of clinical endocrinology and metabolism · 2026Article
- Associations between prenatal per- and polyfluoroalkyl substances (PFAS) and repeated measures of bioactive lipids during pregnancy in the LIFECODES cohort.The Science of the total environment · 2026Article
- Legacy, alternative, and precursor PFAS and associations with lipids and liver function biomarkers: results from a cross-sectional analysis of adult females in the MIREC-ENDO study.International journal of hygiene and environmental health · 2025Article
- PFC/PFAS concentrations in human milk and infant exposure through lactation: a comprehensive review of the scientific literature.Archives of toxicology · 2025Review
- Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and their influence on inflammatory biomarkers in pregnancy: Findings from the LIFECODES cohort.Environment international · 2024Article
- Serum concentrations of legacy, alternative, and precursor per- and polyfluoroalkyl substances: a descriptive analysis of adult female participants in the MIREC-ENDO study.Environmental health : a global access science source · 2024Article
- Concentrations and association between exposure to mixed perfluoroalkyl and polyfluoroalkyl substances and glycometabolism among adolescents.Annals of medicine · 2023Article
- Systematic Evidence Mapping of Potential Exposure Pathways for Per- and Polyfluoroalkyl Substances Based on Measured Occurrence in Multiple Media.Environmental science & technology · 2023Review
- Perspective: Human Milk Composition and Related Data for National Health and Nutrition Monitoring and Related Research.Advances in nutrition (Bethesda, Md.) · 2022Article
- Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research.Environmental toxicology and chemistry · 2021Review
- Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review protocol.Environment international · 2021Article
- Advancing systematic-review methodology in exposure science for environmental health decision making.Journal of exposure science & environmental epidemiology · 2020Article
- Dynamics of associations between perfluoroalkyl substances and uric acid across the various stages of glomerular function.Environmental science and pollution research international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewPer- and polyfluorinated alkyl substances (PFASs) are synthetic chemicals widely detected in human serum, and at low levels in breast milk. We conducted a rapid systematic review on breastfeeding practices and serum concentrations of PFASs-specifically PFOS and PFOA-among reproductive-aged women and young children using the Navigation Guide systematic review methodology. RECENT
findingsWe included 14 studies examining associations between breastfeeding and PFASs in infants/toddlers or pregnant/postnatal women. Breastfeeding was significantly associated with lower PFASs exposure among women and higher PFASs exposure among children. We concluded there was "sufficient" evidence supporting an association between breastfeeding and serum PFASs concentrations among women, and "limited" evidence of an association among children due to issues with sample size, confounding, and exposure assessment. These findings reinforce that lactation is an important excretion route of PFASs for women, and that breast milk may be an important exposure pathway for young children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.