Evidence map›Paper›PMID 29737237›Full record

ReviewTissue engineering. Part B, Reviews2018

Blood Plasma Derivatives for Tissue Engineering and Regenerative Medicine Therapies.

Sara Catarina Nunes da Silva Santos, Ólafur Eysteinn Sigurjonsson, Catarina de Almeida Custódio, João Filipe Colardelle da Luz Mano

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  16. JBRA assisted reproduction · 2024
    Article
  17. Article
  18. Strategies for promoting tendon-bone healing: Current status and prospects.Frontiers in bioengineering and biotechnology · 2023
    Review
  19. A review of platelet-rich plasma for enteric fistula management.Frontiers in bioengineering and biotechnology · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara Catarina Nunes da Silva Santos1 Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro , Campus Universitário de Santiago, Aveiro, Portugal .
Ólafur Eysteinn Sigurjonsson2 The Blood Bank, Landspitali University Hospital , Reykjavik, Iceland .
Catarina de Almeida Custódio1 Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro , Campus Universitário de Santiago, Aveiro, Portugal .
João Filipe Colardelle da Luz Mano1 Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro , Campus Universitário de Santiago, Aveiro, Portugal .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions.

Indexed as

AnimalsBlood PlateletsHumansPlatelet-Rich PlasmaRegenerative Medicinepersonalized medicineplatelet lysatesplatelet-rich plasmaplatelets

Identifiers

PMID29737237
PMCPMC6443031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.