Evidence map›Paper›PMID 29737201›Full record

ArticleCell transplantation2018

Effects of Cryopreservation Duration on the Outcome of Single-Unit Cord Blood Transplantation.

Tang-Her Jaing, Shih-Hsiang Chen, Yu-Chuan Wen, Tsung-Yen Chang, Ya-Chun Yang, Pei-Kwei Tsay

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tang-Her Jaing1 Division of Hematology and Oncology, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan.
Shih-Hsiang Chen1 Division of Hematology and Oncology, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan.
Yu-Chuan Wen3 Department of Nursing, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Tsung-Yen Chang1 Division of Hematology and Oncology, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan.
Ya-Chun Yang3 Department of Nursing, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Pei-Kwei Tsay2 Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryopreservation is widely used in umbilical cord blood (UCB) banking, yet its impact on progenitor cell function remains largely unaddressed. It is unknown whether long-term cryopreservation affects UCB transplantation outcomes. Herein, we evaluated the impact of UCB age on clinical outcomes and investigated the effect of cryopreservation duration of UCB on hematopoietic potency in 91 patients receiving single cord blood transplantations. UCB cryopreservation duration was 0.7 to 13.4 y. The most common indication of transplant was thalassemia (48%). There was no significant association between cryopreservation duration and neutrophil engraftment probability ( P = 0.475). Cryopreservation duration did not affect the post-thaw viability and subsequent neutrophil engraftment rate. Therefore, UCB units can undergo cryopreservation for at least 8 y with no impact on clinical outcomes.

Indexed as

Blood BanksCell SurvivalCord Blood Stem Cell TransplantationCryopreservationFetal BloodHumanscryopreservationtransplantationumbilical cord blood

Identifiers

PMID29737201
PMCPMC6038043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.