ReviewProtein & cell2018
Oral microbiomes: more and more importance in oral cavity and whole body.
Review in Protein & cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05138484 (Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract and Its Role in Reducing Oral Biofilm and Gingival Inflammation. A Randomized, Triple Masked Clinical Trial.), which is not on this map. Cited by 426 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract and Its Role in Reducing Oral Biofilm and Gingival Inflammation. A Randomized, Triple Masked Clinical Trial.
Who cites it
426 citing papers in PubMed, 7 syntheses or guidelines pooled it, 758 citations in OpenAlex.
- Alterations of oral microbiome in oral potentially malignant disorders: a systematic review.BMC oral health · 2026Pooled it
- Prevalence of xerostomia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Influence of Inflammation, Gut Microbiota, and Stress on Cognition and Oral Health Therapies.Current Alzheimer research · 2025Pooled it
- Correlation of Porphyromonas gingivalis with esophageal squamous cell carcinoma: a systematic review.Clinical oral investigations · 2024Pooled it
- Influence of elastomeric and steel ligatures on periodontal health during fixed appliance orthodontic treatment: a systematic review and meta-analysis.Progress in orthodontics · 2024Pooled it
- Extensive comparison of salivary collection, transportation, preparation, and storage methods: a systematic review.BMC oral health · 2024Pooled it
- Does Oral Microbiota Have a Close Relationship with Pancreatic Cancer? A Systematic Review and Meta-Analysis.Annals of surgical oncology · 2023Pooled it
- Sex-specific differences in salivary microbiota composition and their associations with metabolic health in adults with excess body weight: a secondary cross-sectional analysis.Clinical oral investigations · 2026Trial
- Effectiveness of Glycyrrhiza uralensis extract on periodontal pathogens: a randomized controlled clinical trial.BMC oral health · 2025Trial
- Microbiota and head and neck cancers: Mechanistic insights and translational potential.Virulence · 2026Review
- A dual-marker approach for forensic age prediction: integrating the salivary microbiome and antibiotic resistome.International journal of legal medicine · 2026Article
- Article
- Role of Oral-Lung Infection Axis on Respiratory Health.Biomedicines · 2026Review
- Holobiontic Intercellular Relationships Between the Oral Cavity and the Rest of the Human Organism: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Dysbiosis of oral bacteriome and mycobiome associated with the severity of heart failure.BMC oral health · 2026Article
- Effects of Oral Care Intervention on Gingivitis-Mediated Induction of Nitric Oxide Synthesis and Oxidative Stress.International journal of molecular sciences · 2026Article
- Sweet Saliva Trial: Exploratory Evaluation of Salivary Microbiome Responses to Three Thai Desserts.Life (Basel, Switzerland) · 2026Article
- Hydroxyapatite-Based 3D Tooth Models for Investigating Spatially Resolved Analysis of Biofilm Formation Dynamics.ACS applied bio materials · 2026Article
- Review
- Exploring the Therapeutic Potential of Diverse Bacterial Strains for Management of Periodontal Diseases.Probiotics and antimicrobial proteins · 2026Review
366 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats. Synergy and interaction of variable oral microorganisms help human body against invasion of undesirable stimulation outside. However, imbalance of microbial flora contributes to oral diseases and systemic diseases. Oral microbiomes play an important role in the human microbial community and human health. The use of recently developed molecular methods has greatly expanded our knowledge of the composition and function of the oral microbiome in health and disease. Studies in oral microbiomes and their interactions with microbiomes in variable body sites and variable health condition are critical in our cognition of our body and how to make effect on human health improvement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.