ReviewPlanta2018
In vitro plant tissue culture: means for production of biological active compounds.
Review in Planta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
162 citing papers in PubMed.
- Inhibition of melanogenesis byInternational journal of medical sciences · 2021Trial
- Enhanced polyphenolic production in tissue culture-derived Opuntia ficus-indica increases larvicidal activity against Spodoptera exigua: biochemical, histological and molecular docking evidence.Scientific reports · 2026Article
- Influence of the In Vitro Culture System on the Preferential Accumulation of Bioactive Compounds inPlants (Basel, Switzerland) · 2026Article
- Species-Specific Metabolic Identities Persist in Fabaceae Callus Cultures Under Standardized Culture Conditions.Plants (Basel, Switzerland) · 2026Article
- Integrated in vitro regeneration and ex vitro establishment of Syngonium podophyllum 'Pink Allusion': optimization of growth regulators and acclimatization substrates.BMC plant biology · 2026Article
- A high-throughput heterologous expression platform for plant synthetic biology based on Arabidopsis suspension cells.Journal of experimental botany · 2026Article
- In Vitro Culture, Genetic Uniformity Assessment, and Biochemical Traits ofPlants (Basel, Switzerland) · 2026Article
- Lavandin cell extract enriched in rosmarinic acid attenuates inflammation via AMPK/Nrf2/HO-1 activation and IKK/IκB/NF-κB inhibition.BMC plant biology · 2026Article
- Bioreactor Technology for Medicinal Plant In Vitro Cultures: Systems, Applications, and Future Perspectives.Biology · 2026Review
- Immersion Frequency Optimisation and Species-Specific Metabolic Profiles of Colchicum autumnale and Colchicum bivonae in Temporary Immersion Systems.Plants (Basel, Switzerland) · 2026Article
- An in vitro slow-growth callus conservation strategy for several medicinal plants using response surface methodology and machine learning.BMC biotechnology · 2026Article
- Differential effects of biologically and chemically synthesized copper oxide nanoparticles on artemisinin biosynthesis gene expression in Artemisia absinthium.Scientific reports · 2026Article
- Article
- 2-Hydroxy-4-Methoxybenzaldehyde (2H4MB): Integrating Cell Culture, Metabolic Engineering, and Intelligent Genome Editing.International journal of molecular sciences · 2026Review
- Optimized Protocol for Sorghum Regeneration: Enhancing Embryogenic Callus Formation from Immature Inflorescences.Recent patents on biotechnology · 2026Article
- Culture System and Nutrient Restriction Shape Antioxidant Activity inPlants (Basel, Switzerland) · 2025Article
- A comprehensive evaluation of metabolically engineered Cynara cardunculus calli as platform for valuable fatty acid derivatives production.Scientific reports · 2025Article
- Influence of silver nanoparticles on the in vitro growth, phenolic profile, antioxidant potential, enzyme inhibition, and essential oil composition of Clinopodium nepeta subsp. spruneri (Boiss.) Bartolucci & F. Conti.Scientific reports · 2025Article
- Selenium and zinc oxide nanoparticles stimulate product quality, phenolic content, antioxidant activity, and shikonin production in Italian bugloss (Echium italicum L) plantlets under in vitro conditions.BMC plant biology · 2025Article
- Production of Bioactive Compounds inPlants (Basel, Switzerland) · 2025Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
MAIN
conclusionPlant tissue culture as an important tool for the continuous production of active compounds including secondary metabolites and engineered molecules. Novel methods (gene editing, abiotic stress) can improve the technique. Humans have a long history of reliance on plants for a supply of food, shelter and, most importantly, medicine. Current-day pharmaceuticals are typically based on plant-derived metabolites, with new products being discovered constantly. Nevertheless, the consistent and uniform supply of plant pharmaceuticals has often been compromised. One alternative for the production of important plant active compounds is in vitro plant tissue culture, as it assures independence from geographical conditions by eliminating the need to rely on wild plants. Plant transformation also allows the further use of plants for the production of engineered compounds, such as vaccines and multiple pharmaceuticals. This review summarizes the important bioactive compounds currently produced by plant tissue culture and the fundamental methods and plants employed for their production.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.